Capurso Gabriele, Archibugi Livia, Pasquali Piera, Aceti Alessandro, Balducci Paolo, Bianchi Patrizia, Buono Francesco, Camerucci Stefano, Cantarini Rosanna, Centofanti Sergio, Colantonio Patrizia, Cremaschi Riccarda, Crescenzi Sergio, Di Mauro Caterina, Di Renzi Davide, Filabozzi Andrea, Fiorillo Alfonso, Giancaspro Giuseppe, Giovannetti Paola, Lanna Giuseppe, Medori Claudio, Merletti Emilio, Nunnari Enzo, Paris Francesca, Pavone Marco, Piacenti Angela, Rossi Almerindo, Scamuffa Maria Cristina, Spinelli Giovanni, Taborchi Marco, Valente Biagio, Villanova Antonella, Chiriatti Alberto, Delle Fave Gianfranco
Digestive and Liver Disease Unit, S. Andrea Hospital, University Sapienza, Rome, Italy.
Digestive and Liver Disease Unit, S. Andrea Hospital, University Sapienza, Rome, Italy.
Dig Liver Dis. 2017 May;49(5):535-539. doi: 10.1016/j.dld.2016.12.024. Epub 2016 Dec 27.
Data on chronic pancreatitis prevalence are scanty and usually limited to hospital-based studies.
Investigating chronic pancreatitis prevalence in primary care.
Participating primary care physicians reported the prevalence of chronic pancreatitis among their registered patients, environmental factors and disease characteristics. The data were centrally reviewed and chronic pancreatitis cases defined according to M-ANNHEIM criteria for diagnosis and severity and TIGAR-O classification for etiology.
Twenty-three primary care physicians participated in the study. According to their judgment, 51 of 36.401 patients had chronic pancreatitis. After reviewing each patient data, 11 turned out to have definite, 5 probable, 19 borderline and 16 uncertain disease. Prevalence was 30.2/100.000 for definite cases and 44.0/100.000 for definite plus probable cases. Of the 16 patients with definite/probable diagnosis, 8 were male, with mean age of 55.6 (±16.7). Four patients had alcoholic etiology, 5 post-acute/recurrent pancreatitis, 6 were deemed to be idiopathic. Four had pancreatic exocrine insufficiency, 10 were receiving pancreatic enzymes, and six had pain. Most patients had initial stage and non-severe disease.
This is the first study investigating the prevalence of chronic pancreatitis in primary care. Results suggest that the prevalence in this context is higher than in hospital-based studies, with specific features, possibly representing an earlier disease stage.
关于慢性胰腺炎患病率的数据稀少，且通常局限于基于医院的研究。
调查初级保健中慢性胰腺炎的患病率。
参与研究的初级保健医生报告其登记患者中慢性胰腺炎的患病率、环境因素和疾病特征。数据进行集中审核，慢性胰腺炎病例根据M-ANNHEIM诊断和严重程度标准以及TIGAR-O病因分类进行定义。
23名初级保健医生参与了该研究。根据他们的判断，36401名患者中有51名患有慢性胰腺炎。在审核每位患者的数据后，结果显示有11名确诊，5名可能患有，19名临界，16名情况不明。确诊病例的患病率为30.2/100000，确诊加可能病例的患病率为44.0/100000。在16名确诊/可能诊断的患者中，8名男性，平均年龄55.6岁（±16.7）。4名患者病因是酒精性，5名是急性/复发性胰腺炎后，6名被认为是特发性。4名有胰腺外分泌功能不全，10名正在接受胰酶治疗，6名有疼痛。大多数患者处于疾病初期且病情不严重。
这是第一项调查初级保健中慢性胰腺炎患病率的研究。结果表明，在此背景下的患病率高于基于医院的研究，具有特定特征，可能代表疾病的早期阶段。
