成骨不全症患者的进行性双侧椎动脉夹层形成病例

Progressive Bilateral Vertebral Artery Dissection in a Case of Osteogenesis Imperfecta.

作者信息

Kato Yuji, Nagoya Harumitsu, Abe Tetsuya, Hayashi Takeshi, Yasuda Masanori, Uchino Akira, Tanahashi Norio, Takao Masaki

机构信息

Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.

出版信息

J Stroke Cerebrovasc Dis. 2017 Mar;26(3):e43-e46. doi: 10.1016/j.jstrokecerebrovasdis.2016.12.012. Epub 2017 Jan 11.

DOI:10.1016/j.jstrokecerebrovasdis.2016.12.012

PMID:28089253

Abstract

A 32-year-old woman with osteogenesis imperfecta (OI) was admitted to the hospital because of a right-sided occipital headache and facial paresthesia. She was diagnosed with lateral medullary syndrome due to right vertebral artery (VA) dissection. She was treated conservatively without antithrombotic therapy. She developed subarachnoid hemorrhage because of contralateral VA dissection 18 days later. This clinical course may reflect the underlying weakness of the vessel wall in OI. In patients with OI, occlusion of a unilateral VA could cause dissection and subsequent rupture of the contralateral VA. Early surgical treatment for lesions of the VA is required in such cases.

摘要

一名32岁的成骨不全（OI）女性因右侧枕部头痛和面部感觉异常入院。她被诊断为右侧椎动脉（VA）夹层导致的延髓外侧综合征。她接受了保守治疗，未进行抗血栓治疗。18天后，她因对侧VA夹层发生了蛛网膜下腔出血。这一临床过程可能反映了OI患者血管壁的潜在薄弱。在OI患者中，单侧VA闭塞可能导致对侧VA夹层并随后破裂。在这种情况下，需要对VA病变进行早期手术治疗。