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麻醉医生进行的术中聚焦经胸超声心动图对血流动力学不稳定的高危非心脏手术患者管理的影响

Impact of Focused Intraoperative Transthoracic Echocardiography by Anesthesiologists on Management in Hemodynamically Unstable High-Risk Noncardiac Surgery Patients.

作者信息

Kratz Thomas, Steinfeldt Thorsten, Exner Maik, Dell Orto Marco Campo, Timmesfeld Nina, Kratz Caroline, Skrodzki Martin, Wulf Hinnerk, Zoremba Martin

机构信息

Department of Anesthesia and Intensive Care Medicine, Philipps-University of Marburg, Marburg, Germany.

Department of Anesthesia and Intensive Care Medicine, Philipps-University of Marburg, Marburg, Germany.

出版信息

J Cardiothorac Vasc Anesth. 2017 Apr;31(2):602-609. doi: 10.1053/j.jvca.2016.11.002. Epub 2016 Nov 2.

DOI:10.1053/j.jvca.2016.11.002
PMID:28089598
Abstract

OBJECTIVES

Focused transthoracic echocardiography (TTE) is used perioperatively for surgical patients. Intraoperative application of TTE is feasible, but its benefits remain unclear. The intention of this study was to investigate the effect of intraoperative TTE on the management of high-risk noncardiac surgery patients.

DESIGN

A prospective interventional study.

SETTING

Single-center university hospital.

PARTICIPANTS

Fifty consecutive hemodynamically unstable high-risk patients anesthetized for noncardiac surgery.

INTERVENTIONS

Focused TTE was performed on hemodynamically unstable anesthetized patients whenever circulatory instability (defined as hypotension or low cardiac output) occurred intraoperatively. A cardiac output monitoring system using pulse contour analysis was established before induction of anesthesia. The intended therapy for stabilizing the patient was documented; however, the management actually administered was guided by the results of the TTE. Differences between the 2 lines of management were documented and analyzed.

MEASUREMENTS AND MAIN RESULTS

Intraoperative TTE was applied successfully in all 50 unstable patients. In 33 patients (66%, 95% confidence interval, 52.11-77.61) TTE led to a change of management. Altogether, 82 episodes of hemodynamic instability were recorded, including 38 episodes (46.34%, 95% confidence interval, 35.95-57.06) in which TTE led to a change of treatment. The most common pathologic finding was hypovolemia (66%); in contrast, in 22%, right-heart overload or right-heart failure (4%) was detected.

CONCLUSIONS

Focused TTE by anesthesiologists can provide new information that may alter the hemodynamic management of unstable high-risk noncardiac surgery patients in the operating room.

摘要

目的

聚焦式经胸超声心动图(TTE)用于手术患者围手术期。TTE在术中的应用是可行的,但其益处仍不明确。本研究旨在探讨术中TTE对高危非心脏手术患者管理的影响。

设计

前瞻性干预研究。

地点

单中心大学医院。

参与者

连续50例因非心脏手术而麻醉的血流动力学不稳定的高危患者。

干预措施

只要术中出现循环不稳定(定义为低血压或低心输出量),就对血流动力学不稳定的麻醉患者进行聚焦式TTE检查。在麻醉诱导前建立使用脉搏轮廓分析的心输出量监测系统。记录稳定患者的预期治疗方法;然而,实际实施的管理由TTE结果指导。记录并分析两种管理方式之间的差异。

测量指标和主要结果

术中TTE在所有50例不稳定患者中均成功应用。在33例患者(66%,95%置信区间,52.11 - 77.61)中,TTE导致了管理方式的改变。总共记录了82次血流动力学不稳定事件,其中38次(46.34%,95%置信区间,35.95 - 57.06)TTE导致了治疗方式的改变。最常见的病理发现是血容量不足(66%);相比之下,22%检测到右心负荷过重或右心衰竭(4%)。

结论

麻醉医生进行的聚焦式TTE可提供新信息,可能改变手术室中不稳定高危非心脏手术患者的血流动力学管理。

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