Hataya Yuji, Oba Akifumi, Yamashita Takafumi, Komatsu Yasato
Department of Endocrinology, Kyoto City Hospital, Japan.
Intern Med. 2017;56(2):175-179. doi: 10.2169/internalmedicine.56.6438. Epub 2017 Jan 15.
Hyponatremia is one of the most common electrolyte disorders encountered in the elderly. We present the case of an 81-year-old man who developed hyponatremia due to isolated hypoaldosteronism occurring after licorice withdrawal. He had severe hypokalemia with hypertension and was diagnosed with pseudoaldosteronism. He had been taking a very small dose of licorice as a mouth refresher since his early adulthood. Five months after licorice withdrawal, he developed hypovolemic hyponatremia, which was resolved with administration of fludrocortisone acetate. Our experience with this case suggests that isolated hypoaldosteronism occurring after licorice withdrawal should be considered as a potential cause of hyponatremia in elderly patients.
低钠血症是老年人中最常见的电解质紊乱之一。我们报告一例81岁男性，因停用甘草后发生孤立性醛固酮缺乏症而出现低钠血症。他患有严重低钾血症伴高血压，被诊断为假性醛固酮增多症。自成年早期以来，他一直服用极少量甘草作为口腔清新剂。停用甘草五个月后，他出现低血容量性低钠血症，经醋酸氟氢可的松治疗后得以缓解。我们对该病例的经验表明，停用甘草后发生的孤立性醛固酮缺乏症应被视为老年患者低钠血症的潜在原因。
