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电子采集的患者报告的身体功能:肥胖医学中的一项重要生命体征。

Electronically captured, patient-reported physical function: an important vital sign in obesity medicine.

作者信息

Fleming J, Wood G C, Seiler C, Cook A, Lent M R, Still C D, Benotti P N, Irving B A

机构信息

Obesity Institute Geisinger Health System Danville PA USA.

Obesity Institute Geisinger Health System Danville PA USA; School of Kinesiology Louisiana State University Baton Rouge LA USA.

出版信息

Obes Sci Pract. 2016 Dec;2(4):399-406. doi: 10.1002/osp4.67. Epub 2016 Sep 20.

Abstract

OBJECTIVES

Impaired physical function (i.e., inability to walk 200 feet, climb a flight of stairs or perform activities of daily living) predicts poor clinical outcomes and adversely impacts medical and surgical weight management. However, routine assessment physical function is seldom performed clinically. The PROMIS Physical Function Short Form 20a (SF-20a) is a validated questionnaire for assessing patient reported physical function, which includes published T-score percentiles adjusted for gender, age and education. However, the effect that increasing levels of obesity has on these percentiles is unclear. We hypothesized that physical function would decline with increasing level of obesity independent of gender, age, education and comorbidity.

MATERIALS AND METHODS

This study included 1,627 consecutive weight management patients [(mean ± SEM), 44.7 ± 0.3 years and 45.1 ± 0.2 kg/m] that completed the PROMIS SF-20a during their initial consultation. We evaluated the association between obesity level and PROMIS T-score percentiles using multiple linear regression adjusting for gender, age, education and Charlson Comorbidity Index (CCI).

RESULTS

Multiple linear regression T-score percentiles were lower in obesity class 2 (-12.4%tile,  < 0.0001), class 3 (-17.0%tile,  < 0.0001) and super obesity (-25.1%tile,  < 0.0001) compared to class 1 obesity.

CONCLUSION

In patients referred for weight management, patient reported physical function was progressively lower in a dose-dependent fashion with increasing levels of obesity, independent of gender, age, education and CCI.

摘要

目的

身体功能受损(即无法行走200英尺、爬一段楼梯或进行日常生活活动)预示着临床预后不良,并对医学和手术体重管理产生不利影响。然而,临床上很少对身体功能进行常规评估。患者报告结果测量信息系统身体功能简表20a(SF - 20a)是一种经过验证的用于评估患者报告的身体功能的问卷,其中包括根据性别、年龄和教育程度调整后的已发表T分数百分位数。然而,肥胖程度增加对这些百分位数的影响尚不清楚。我们假设,身体功能会随着肥胖程度的增加而下降,且不受性别、年龄、教育程度和合并症的影响。

材料与方法

本研究纳入了1627例连续的体重管理患者[(均值±标准误),44.7±0.3岁,体重指数为45.1±0.2kg/m²],这些患者在初次咨询时完成了患者报告结果测量信息系统SF - 20a问卷。我们使用多线性回归评估肥胖程度与患者报告结果测量信息系统T分数百分位数之间的关联,并对性别、年龄、教育程度和查尔森合并症指数(CCI)进行了调整。

结果

与1级肥胖相比,2级肥胖(-12.4百分位数,P<0.0001)、3级肥胖(-17.0百分位数,P<0.0001)和超级肥胖(-25.1百分位数,P<0.0001)的多线性回归T分数百分位数更低。

结论

在转诊进行体重管理的患者中,患者报告的身体功能随着肥胖程度的增加呈剂量依赖性逐渐降低,且不受性别、年龄、教育程度和查尔森合并症指数的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb39/5523721/f44d362ad514/OSP4-2-399-g001.jpg

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