Hartl E, Rémi J, Stoyke C, Noachtar S
Department of Neurology, Epilepsy Center, University of Munich, Munich, Germany.
Acta Neurol Scand. 2017 Aug;136(2):160-163. doi: 10.1111/ane.12730. Epub 2017 Jan 16.
Periodic discharges (PDs) are well established as either periodic lateralized epileptiform discharges (LPDs) or generalized discharges. However, PDs in the midline can currently not be adequately classified as they are not generalized and not lateralized.
To propose a modification of the current LPD classification.
We here present a paradigmatic case series of three adult patients with midline LPDs.
In our patients, ictal electroencephalography (EEG) recordings revealed periodic epileptiform discharges in the midline region. All three patients were non-lesional.
We, thus, suggest to include periodic localized non-lateralized epileptiform discharges into the term LPDs (in addition to periodic lateralized epileptiform discharges), as they can also be recorded as localized EEG phenomenon in the midline region.
周期性放电(PDs)已被明确分为周期性一侧性癫痫样放电(LPDs)或全身性放电。然而,中线部位的PDs目前无法得到充分分类,因为它们既不是全身性的也不是一侧性的。
提出对当前LPD分类的修改建议。
我们在此展示了3例患有中线LPDs的成年患者的典型病例系列。
在我们的患者中,发作期脑电图(EEG)记录显示中线区域有周期性癫痫样放电。所有3例患者均无病灶。
因此,我们建议将周期性局限性非一侧性癫痫样放电纳入LPDs这一术语中(除周期性一侧性癫痫样放电外),因为它们也可作为中线区域的局限性脑电图现象被记录到。