Zorn B, Chitrit Y, Lebo J D, Giacomini T, Godefroy Y, Galet B
Service de Gynécologie-Obstétrique, Centre Hospitalier Robert-Ballanger, Aulnay-sous-Bois.
J Gynecol Obstet Biol Reprod (Paris). 1989;18(5):627-34.
Most studies have been concerned with recovering Chlamydia trachomatis (CT) from the endocervix on the one hand and from the adnexae on the other hand and consider its relationship to infection of the upper genital tract. Our work is concerned with the endometrium. 42 women were examined: 22 of them had salpingitis (group I), 14 were considered possibly to have endometritis with a risk of infection with CT, or had cervicitis (group II), and 6 were in the control group (group III). Samples were taken from the endometrium that had been removed for histological examination and for searching for CT in cultures. These samples were taken routinely at the initial examination and then again 10 and/or 40 days later for women in groups I and II. These latter were all treated systemically with cyclines. A high incidence of endometrial infection with CT was found (17%). The recovery of CT from the endometrium was correlated with the presence of an intra-uterine device, with purulent discharge, with evidence of CT in the cervix, and with anti-chlamydia serology higher than or equal to 1/128. CT infection of the endometrium gave late lesions of endometritis which persisted in spite of the antibiotic therapy that had been given.
大多数研究一方面关注从宫颈管内膜分离沙眼衣原体（CT），另一方面关注从附件分离沙眼衣原体，并探讨其与上生殖道感染的关系。我们的研究关注的是子宫内膜。对42名女性进行了检查：其中22名患有输卵管炎（第一组），14名被认为可能患有子宫内膜炎且有感染CT的风险，或患有宫颈炎（第二组），6名作为对照组（第三组）。从因组织学检查和培养查找CT而切除的子宫内膜中取样。这些样本在初次检查时常规采集，然后第一组和第二组的女性在10天和/或40天后再次采集。后者均接受了四环素类药物的全身治疗。发现子宫内膜CT感染的发生率很高（17%）。从子宫内膜中分离出CT与宫内节育器的存在、脓性分泌物、宫颈管内膜有CT证据以及抗衣原体血清学高于或等于1/128相关。子宫内膜的CT感染导致了子宫内膜炎的晚期病变，尽管给予了抗生素治疗，这些病变仍持续存在。
