Kobayashi M
J Invertebr Pathol. 1989 Nov;54(3):379-84. doi: 10.1016/0022-2011(89)90122-5.
Effect of a supraoptimal temperature on the accumulation of virus-specific translatable mRNAs was examined in the larvae of the silkworm. Bombyx mori, infected with Bombyx densonucleosis virus type 2. The results showed that incubation of infected larvae at 35 degrees C resulted in a rapid and selective decrease in the virus-specific translatable mRNAs which preexisted in the infected midgut. Upon temperature-shift from 35 degrees to 25 degrees C, the virus-specific translatable mRNAs became clearly observed within 12 hr. These results indicate that a supraoptimal temperature restricts the accumulation of virus-specific translatable mRNAs. Both rapid decay and suppressed synthesis might be responsible for the selective restriction of virus-specific translatable mRNA accumulation at a supraoptimal temperature.
在感染了2型家蚕浓核症病毒的家蚕幼虫中，研究了超适温度对病毒特异性可翻译mRNA积累的影响。结果表明，将感染的幼虫在35℃下培养，导致感染中肠中预先存在的病毒特异性可翻译mRNA迅速且选择性地减少。当温度从35℃转变为25℃时，在12小时内可清晰观察到病毒特异性可翻译mRNA。这些结果表明，超适温度会限制病毒特异性可翻译mRNA的积累。快速降解和合成受抑制可能是超适温度下病毒特异性可翻译mRNA积累受到选择性限制的原因。
