Erhard Daniela M, Nguyen Sarah, Guy Katelyn J, Casalaz Dan M, König Kai
Department of Paediatrics, Mercy Hospital for Women, 163 Studley Road, Melbourne, VIC, 3084, Australia.
Eur J Pediatr. 2017 Mar;176(3):407-411. doi: 10.1007/s00431-017-2854-7. Epub 2017 Jan 16.
We investigated dwell times and risk of non-elective removal of 975 single-lumen 1-French peripherally inserted central catheters (1FR-PICC) according to tip position in a cohort of very preterm infants with a mean (SD) gestational age of 27 (2) weeks and a mean (SD) birth weight of 988 (294) g over an eight-year period. Infants with a 1FR-PICC inserted for continuous infusion of intravenous fluids within the first 30 days of life were eligible. Dwell times of PICC with elective versus non-elective removal, risk of non-elective removal of PICC according to tip position, and differences between upper versus lower limb catheter insertion were analysed. 33.8% PICC were removed non-electively. Median (IQR) dwell time was 193 (142-287) versus 154 (102-260) h for elective versus non-elective removal (p < 0.001). Non-elective removal was more common for lower limb insertion sites: 41 versus 31% (p = 0.002). PICC were significantly more likely to be removed non-electively when located in the axillary (odds ratio (OR) 2.08), cephalic (OR 8.93), external iliac (OR 4.99), and femoral (OR 10.31) vein.
In this cohort, dwell times of 1FR-PICC lines removed non-electively were similar to 1.9- or 2.0FR-PICC. PICC tips positioned in the axillary, cephalic, external iliac, and femoral veins had a higher risk of non-elective removal. What is Known: •Peripherally inserted central catheters (PICC) are widely used in neonatal intensive care. •Previous studies focused on 2-French PICC and newborns of all gestational ages. What is New: •Dwell times of 1-French PICC removed non-electively were similar to 2-French PICC. •1-French PICC tips positioned more peripherally had a higher risk of non-elective removal.
我们在一个平均(标准差)胎龄为27(2)周、平均(标准差)出生体重为988(294)克的极早产儿队列中,根据尖端位置对975根单腔1法国规格的外周静脉穿刺中心静脉导管(1FR - PICC)的留置时间和非选择性拔除风险进行了为期八年的研究。在出生后30天内插入1FR - PICC用于持续静脉输液的婴儿符合条件。分析了选择性拔除与非选择性拔除的PICC的留置时间、根据尖端位置的PICC非选择性拔除风险以及上肢与下肢导管插入之间的差异。33.8%的PICC被非选择性拔除。选择性拔除与非选择性拔除的中位(四分位间距)留置时间分别为193(142 - 287)小时和154(102 - 260)小时(p < 0.001)。下肢插入部位的非选择性拔除更为常见:41%对31%(p = 0.002)。当PICC位于腋静脉(优势比(OR)2.08)、头静脉(OR 8.93)、髂外静脉(OR 4.99)和股静脉(OR 10.31)时,非选择性拔除的可能性显著更高。
在这个队列中,非选择性拔除的1FR - PICC导管的留置时间与1.9或2.0FR - PICC相似。位于腋静脉、头静脉、髂外静脉和股静脉的PICC尖端非选择性拔除的风险更高。已知信息:•外周静脉穿刺中心静脉导管(PICC)在新生儿重症监护中广泛使用。•先前的研究集中在2法国规格的PICC和所有孕周的新生儿。新发现:•非选择性拔除的1法国规格PICC的留置时间与2法国规格PICC相似。•位置更外周的1法国规格PICC尖端非选择性拔除的风险更高。