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急性心肌梗死时完全性房室传导阻滞的即刻预后意义

Immediate prognostic significance of complete atrioventricular block in acute myocardial infarction.

作者信息

Kuo C T, Liu C Y, Hsu T S, Chiang C W, Lee Y S

出版信息

Taiwan Yi Xue Hui Za Zhi. 1989 Jul;88(7):712-7.

PMID:2809563
Abstract

To discern the relative prognostic role of complete atrioventricular block (CAVB) in patients with acute myocardial infarction (AMI), 908 consecutive patients with AMI were studied over a 7-year period. Of the 559 patients with anterior wall AMI, 13 (2.3%) demonstrated CAVB, of whom 10 (76.9%) died in the hospital (vs 10.4% in those without CAVB) (p less than 0.001). In 349 patients with inferior wall AMI, 30 (8.6%) developed CAVB, of whom 6 (20%) died (vs 6.3% in those without CAVB) (p less than 0.01). In anterior wall AMI, all 5 patients with narrow QRS complexes (vs 8/11 with wide QRS complexes) (p = NS) died; in inferior wall AMI, 4/25 with narrow QRS complexes (vs 2/5 with wide QRS complexes) (p = NS) died. The mortality rate of patients with an escape frequency of less than or equal to 50/min did not differ significantly from that of patients with greater than 50/min regardless of the site of infarction or whether a pacemaker was used. In anterior wall AMI, the mortality rate of paced patients was 70% (7/10) compared to 100% (3/3) of non-paced patients (p = NS). In inferior wall AMI, the mortality rate of paced (5/25) and non-paced (1/5) patients was both 20%. Thus, none of the clinical parameters such as escape rhythm, the width of escape QRS complexes and pacemaker therapy discriminated the survivors from the deaths. In anterior wall AMI, episodes of cardiac standstill or bradycardia were of short duration, and pacemaker therapy was only one of the therapies applied.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为了明确完全性房室传导阻滞(CAVB)在急性心肌梗死(AMI)患者中的相对预后作用,我们在7年时间里对908例连续的AMI患者进行了研究。在559例前壁AMI患者中,13例(2.3%)出现了CAVB,其中10例(76.9%)在医院死亡(无CAVB者为10.4%)(p<0.001)。在349例下壁AMI患者中,30例(8.6%)发生了CAVB,其中6例(20%)死亡(无CAVB者为6.3%)(p<0.01)。在前壁AMI中,所有5例QRS波群狭窄的患者(相对11例QRS波群增宽患者中的8例)(p=无显著性差异)均死亡;在下壁AMI中,25例QRS波群狭窄患者中有4例(相对5例QRS波群增宽患者中的2例)(p=无显著性差异)死亡。逸搏频率小于或等于50次/分钟的患者死亡率与大于50次/分钟的患者相比,无论梗死部位或是否使用起搏器,均无显著差异。在前壁AMI中,使用起搏器患者的死亡率为70%(7/10),而非起搏器患者为100%(3/3)(p=无显著性差异)。在下壁AMI中,使用起搏器(5/25)和未使用起搏器(1/5)患者的死亡率均为20%。因此,诸如逸搏心律、逸搏QRS波群宽度和起搏器治疗等临床参数均无法区分存活者与死亡者。在前壁AMI中,心脏停搏或心动过缓发作持续时间较短,起搏器治疗只是所应用的治疗方法之一。(摘要截选至250字)

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