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盆腔脏器切除术后采用改良腹直肌肌腹膜瓣(MRAM)进行盆底重建。

Pelvic floor reconstruction by modified rectus abdominis myoperitoneal (MRAM) flap after pelvic exenterations.

作者信息

Cibula D, Zikan M, Fischerova D, Kocian R, Germanova A, Burgetova A, Dusek L, Fartáková Z, Schneiderová M, Nemejcová K, Slama J

机构信息

Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic.

Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic.

出版信息

Gynecol Oncol. 2017 Mar;144(3):558-563. doi: 10.1016/j.ygyno.2017.01.014. Epub 2017 Jan 14.

Abstract

OBJECTIVE

To describe the technique and report experiences with pelvic floor reconstruction by modified rectus abdominis myoperitoneal (MRAM) flap after extensive pelvic procedures.

METHODS

Surgical technique of MRAM harvest and transposition is carefully described. The patients in whom pelvic floor reconstruction with MRAM after either infralevator pelvic exenteration and/or extended lateral pelvic sidewall excision was carried out were enrolled into the study (MRAM group, n=16). Surgical data, post-operative morbidity, and disease status were retrospectively assessed. The results were compared with a historical cohort of patients, in whom an exenterative procedure without pelvic floor reconstruction was performed at the same institution (control group, n=24).

RESULTS

Both groups were balanced in age, BMI, tumor types, and previous treatment. Substantially less patients from the MRAM group required reoperation within 60days of the surgery (25% vs. 50%) which was due to much lower rate of complications potentially related to empty pelvis syndrome (1 vs. 7 reoperations) (p=0.114). Late post-operative complication rate was substantially lower in the MRAM group (any grade: 79% vs. 44%; grade≥3: 37% vs. 6%) (p=0.041). The performance status 6months after the surgery was ≤1 in the majority of patients in MRAM (81%) while in only 38% of patients from the control group (p=0.027). There was one incisional hernia in MRAM group while three cases were reported in the controls.

CONCLUSIONS

Pelvic floor reconstruction by MRAM in patients after pelvic exenterative procedures is associated with a substantial decrease in postoperative complications that are potentially related to empty pelvis syndrome.

摘要

目的

描述改良腹直肌肌腹膜(MRAM)瓣在广泛盆腔手术后进行盆底重建的技术并报告经验。

方法

详细描述了MRAM瓣获取及转移的手术技术。纳入在低位盆腔脏器切除术和/或扩大的盆腔侧壁切除术之后采用MRAM进行盆底重建的患者(MRAM组,n = 16)。对手术数据、术后发病率和疾病状态进行回顾性评估。将结果与在同一机构进行了无盆底重建的脏器切除手术的历史队列患者(对照组,n = 24)进行比较。

结果

两组在年龄、体重指数、肿瘤类型和既往治疗方面均衡。MRAM组在术后60天内需要再次手术的患者明显更少(25%对50%),这是由于与盆腔空虚综合征潜在相关的并发症发生率低得多(再次手术1例对7例)(p = 0.114)。MRAM组术后晚期并发症发生率明显更低(任何级别:79%对44%;≥3级:37%对6%)(p = 0.041)。MRAM组大多数患者术后6个月的体能状态≤1(81%),而对照组仅38%的患者如此(p = 0.027)。MRAM组有1例切口疝,而对照组报告了3例。

结论

盆腔脏器切除术后患者采用MRAM进行盆底重建与潜在与盆腔空虚综合征相关的术后并发症大幅减少相关。

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