在新生儿转运期间，使用依诺昔酮抑制磷酸二酯酶3作为新生儿重度持续性肺动脉高压的一线治疗：一例病例报告。
PDE3 inhibition with enoximone as first-line therapy for severe persistent pulmonary hypertension of the newborn during neonatal transport: a case report.
作者信息
van der Lee Robin, Peels Barbara, Koopman-Esseboom Corine
机构信息
Emma Children's Hospital Academic Medical Center Meibergdreef 15 1105AZ Amsterdam Netherlands.
Wilhelmina Childrens's Hospital University Medical Center Lundlaan 6 3584EA Utrecht Netherlands.
出版信息
Clin Case Rep. 2016 Nov 23;5(1):18-21. doi: 10.1002/ccr3.748. eCollection 2017 Jan.
Abstract
Severe Persistent pulmonary hypertension of the newborn (PPHN) can be effectively treated with a PDE3 inhibitor as first-line treatment during neonatal transport when iNO is not readily available. Starting iNO as soon as possible is strongly advised because of the complementary actions of both therapeutics.
摘要
新生儿持续性肺动脉高压（PPHN）严重时，若一氧化氮（iNO）难以立即获取，在新生儿转运期间，磷酸二酯酶3（PDE3）抑制剂可作为一线治疗有效治疗该病。由于两种治疗方法具有互补作用，强烈建议尽快开始使用iNO。
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