Balbouzis Theodoros, Georgiadis Thomas, Grigoris Peter
Department of Orthopedics, Iaso General Hospital, Athens, Greece.
Laboratory of Pathology, Hygeia General Hospital, Athens, Greece.
Hip Pelvis. 2016 Dec;28(4):249-253. doi: 10.5371/hp.2016.28.4.249. Epub 2016 Dec 28.
A case of a female patient with local and systemic complications of metallosis, following catastrophic wear of a revised hip arthroplasty, is presented. The patient had a history of a fractured ceramic-on-ceramic implant, exchanged with a metal-on-polyethylene prosthesis. Systemic complications included sarcoidosis-like reactions, presenting as granulomatous lung disease, along with chorioretinitis, erythema nodosum, and cardiomyopathy. High local and circulating cobalt and chromium levels established the diagnosis. The patient underwent extensive debridement and implant revision. One year postoperatively, she had no respiratory symptoms or functional impairment. Local and systemic complications of metallosis after hip arthroplasty should be promptly recognized and treated operatively.
本文报告了一例女性患者,在翻修髋关节置换术后发生灾难性磨损,出现金属中毒的局部和全身并发症。该患者曾有陶瓷对陶瓷植入物骨折病史,后更换为金属对聚乙烯假体。全身并发症包括类肉瘤样反应,表现为肉芽肿性肺病,同时伴有脉络膜视网膜炎、结节性红斑和心肌病。高局部和循环钴及铬水平确立了诊断。患者接受了广泛的清创和植入物翻修。术后一年,她没有呼吸症状或功能障碍。髋关节置换术后金属中毒的局部和全身并发症应及时识别并进行手术治疗。