Chehrazi B B, Scremin O, Decima E E
Department of Neurological Surgery, University of California, School of Medicine, Davis, Sacramento.
J Neurosurg. 1989 Nov;71(5 Pt 1):747-53. doi: 10.3171/jns.1989.71.5.0747.
Forty-two cats were subjected to decerebration, thoracic and lumbar laminectomies, and isolation of the sciatic nerves. Spinal evoked potentials in response to bilateral sciatic nerve stimulation were recorded at L-3, and the spinal cord blood flow (SCBF) was measured by the hydrogen clearance technique. Thoracic cordotomy did not alter the lumbar SCBF or the central conduction time as determined by spinal evoked potentials. Thoracic cordotomy significantly lowered the lumbar spinal cord injury threshold. Continuous sciatic nerve stimulation increased the lumbar SCBF in normal and traumatized animals; however, it did not affect the spinal cord injury threshold as measured by recovery of the spinal evoked potentials. It appears that rostral spinal cord integrity is far more significant in recovery from spinal cord injury than the maintenance of regional SCBF.
42只猫接受了去大脑、胸段和腰段椎板切除术以及坐骨神经分离术。在L-3记录双侧坐骨神经刺激引起的脊髓诱发电位，并采用氢清除技术测量脊髓血流量（SCBF）。胸段脊髓切断术并未改变通过脊髓诱发电位测定的腰段SCBF或中枢传导时间。胸段脊髓切断术显著降低了腰段脊髓损伤阈值。持续坐骨神经刺激可增加正常和创伤动物的腰段SCBF；然而，它并未影响通过脊髓诱发电位恢复情况测定的脊髓损伤阈值。似乎脊髓头端的完整性在脊髓损伤恢复中比维持局部SCBF更为重要。
