Dahmani Omar, Sophoclis Christine, Kebir Malika, Bouguern Djemai, Sakho Aboubacry, Demarchi Pascale
Department of Nephrology and Dialysis, Hospital Louis Jaillon, Saint-Claude, France.
Secondary Care, Hospital Louis Jaillon, Saint-Claude, France.
Saudi J Kidney Dis Transpl. 2017 Jan-Feb;28(1):154-157. doi: 10.4103/1319-2442.198239.
The acronym of malignancy, iatrogenic, intoxication and immobilization, sarcoidosis, hyperparathyroidism and hyperthyroidism, milk-alkali syndrome, and paget is very helpful in diagnosing hypercalcemia. We report on a 94-year-old patient with history of end-stage renal failure secondary to benign nephroangiosclerosis, who was on maintenance hemodialysis during dialysis, his blood chemistry revealed mild hypercalcemia (2.66 mmol/L) with normal level of intact primary hyperparathyroidism (32.37 ng/mL) mandating the discontinuation of Vitamin D[3]. In view of persisting hypercalcemia, denosumab 60 mg/mL was administrated subcutaneously. The serum calcium level showed a decrease and stabilized at near upper limit (2.57 mmol/L). Three weeks later, the serum calcium remained mildly elevated fluctuating between 2.66 and 2.80 mmol/L.
恶性肿瘤、医源性因素、中毒与制动、结节病、甲状旁腺功能亢进和甲状腺功能亢进、乳碱综合征以及佩吉特病的英文首字母缩写对于诊断高钙血症非常有帮助。我们报告了一名94岁的患者，其有因良性肾血管硬化导致终末期肾衰竭的病史，在透析期间接受维持性血液透析，其血液化学检查显示轻度高钙血症（2.66 mmol/L），完整甲状旁腺素水平正常（32.37 ng/mL），这就要求停用维生素D[3]。鉴于高钙血症持续存在，皮下注射了60 mg/mL的地诺单抗。血清钙水平下降并稳定在接近上限（2.57 mmol/L）。三周后，血清钙仍轻度升高，在2.66至2.80 mmol/L之间波动。
