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中国猪体内携带mcr-1的肠炎沙门氏菌鼠伤寒血清型34型菌株

mcr-1-Harboring Salmonella enterica Serovar Typhimurium Sequence Type 34 in Pigs, China.

作者信息

Yi Linxian, Wang Jing, Gao Yanling, Liu Yiyun, Doi Yohei, Wu Renjie, Zeng Zhenling, Liang Zisen, Liu Jian-Hua

出版信息

Emerg Infect Dis. 2017 Feb;23(2):291-295. doi: 10.3201/eid2302.161543.

DOI:10.3201/eid2302.161543
PMID:28098547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5324782/
Abstract

We detected the mcr-1 gene in 21 (14.8%) Salmonella isolates from pigs at slaughter; 19 were serovar Typhimurium sequence type 34. The gene was located on IncHI2-like plasmids that also harbored IncF replicons and lacked a conjugative transfer region. These findings highlight the need to prevent further spread of colistin resistance in animals and humans.

摘要

我们在21株（14.8%）屠宰猪的沙门氏菌分离株中检测到了mcr-1基因；其中19株为鼠伤寒血清型序列型34。该基因位于IncHI2样质粒上，这些质粒还含有IncF复制子，且缺乏接合转移区域。这些发现凸显了防止动物和人类中黏菌素耐药性进一步传播的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dfe/5324782/57254357d29e/16-1543-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dfe/5324782/0edf4b62a9f8/16-1543-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dfe/5324782/57254357d29e/16-1543-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dfe/5324782/0edf4b62a9f8/16-1543-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dfe/5324782/57254357d29e/16-1543-F2.jpg

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