• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Late spontaneous decapsulation of the kidney graft in a patient with hepatitis C and treated with sirolimus: possible pathophysiological association in a rare complication.1例丙型肝炎患者肾移植后使用西罗莫司治疗出现晚期自发性肾被膜剥脱：一种罕见并发症可能的病理生理关联
BMJ Case Rep. 2017 Jan 18;2017:bcr2016218335. doi: 10.1136/bcr-2016-218335.
2
Late spontaneous kidney graft decapsulation after administration of sirolimus in a recipient with chronic hepatitis B and C infection: a case report.西罗莫司给药后慢性乙型和丙型肝炎感染受者出现迟发性自发性肾移植包膜剥脱：一例报告
Transplant Proc. 2008 Sep;40(7):2437-9. doi: 10.1016/j.transproceed.2008.07.044.
3
Considerations in sirolimus use in the early and late post-transplant periods.肾移植术后早期和晚期使用西罗莫司的注意事项。
Expert Opin Drug Saf. 2009 Jul;8(4):421-34. doi: 10.1517/14740330903037156.
4
Effect of sirolimus in combination with low-dose cyclosporine and steroids on acute renal allograft rejection.
J Formos Med Assoc. 2003 Feb;102(2):91-6.
5
Sirolimus (rapamycin) reduces the incidence of acute rejection episodes in renal transplantation: an initial experience in Taiwan.
Transplant Proc. 2004 Sep;36(7):2051-2. doi: 10.1016/j.transproceed.2004.08.095.
6
[The first experience with sirolimus (Rapamune) after kidney transplantation in Lithuania].[立陶宛肾移植后使用西罗莫司（雷帕鸣）的首次经验]
Medicina (Kaunas). 2005;41 Suppl 1:93-100.
7
Severe sirolimus-induced acute hepatitis in a renal transplant recipient.肾移植受者中由西罗莫司引起的严重急性肝炎。
Transpl Int. 2010 Sep;23(9):967-70. doi: 10.1111/j.1432-2277.2010.01100.x. Epub 2010 May 20.
8
[Everolimus and azoospermia, a causal relationship? About one case in a renal transplant patient].[依维莫司与无精子症，存在因果关系吗？关于一名肾移植患者的病例]
Nephrol Ther. 2014 Feb;10(1):44-5. doi: 10.1016/j.nephro.2013.09.002. Epub 2013 Dec 25.
9
Conversion to sirolimus for chronic allograft nephropathy and calcineurin inhibitor toxicity and the adverse effects of sirolimus after conversion.转换为西罗莫司治疗慢性移植肾肾病和钙调神经磷酸酶抑制剂毒性以及转换后西罗莫司的不良反应。
Transplant Proc. 2009 Sep;41(7):2789-93. doi: 10.1016/j.transproceed.2009.07.094.
10
Kidney transplantation with sirolimus and mycophenolate mofetil-based immunosuppression: 5-year results of a randomized prospective trial compared to calcineurin inhibitor drugs.肾移植采用西罗莫司和霉酚酸酯为基础的免疫抑制治疗：与钙调神经磷酸酶抑制剂药物相比的随机前瞻性试验5年结果
Transplantation. 2007 Apr 15;83(7):883-92. doi: 10.1097/01.tp.0000258586.52777.4c.

本文引用的文献

1
Lymphatic disorders after renal transplantation: new insights for an old complication.肾移植后的淋巴系统疾病：对一种旧有并发症的新认识
Clin Kidney J. 2015 Oct;8(5):615-22. doi: 10.1093/ckj/sfv064. Epub 2015 Jul 16.
2
Successful treatment of spontaneous kidney graft decapsulation 18 years after renal transplantation: a case report.肾移植18年后成功治疗自发性肾移植包膜剥脱：一例报告
NDT Plus. 2010 Feb;3(1):100-2. doi: 10.1093/ndtplus/sfp148.
3
Late subcapsular lymphocele in a kidney graft.肾移植术后晚期包膜下淋巴囊肿
Transplantation. 2012 Apr 27;93(8):e35-7. doi: 10.1097/TP.0b013e31824cd5c4.
4
Late spontaneous kidney graft decapsulation after administration of sirolimus in a recipient with chronic hepatitis B and C infection: a case report.西罗莫司给药后慢性乙型和丙型肝炎感染受者出现迟发性自发性肾移植包膜剥脱：一例报告
Transplant Proc. 2008 Sep;40(7):2437-9. doi: 10.1016/j.transproceed.2008.07.044.
5
Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis.雷帕霉素哺乳动物靶点的抑制作用会阻碍淋巴管生成。
Kidney Int. 2007 Apr;71(8):771-7. doi: 10.1038/sj.ki.5002112. Epub 2007 Feb 14.
6
Severe ascites following renal transplant biopsy caused by a rupture of a subcapsular lymphocele: treated successfully by retroperitonealization.肾移植活检后因包膜下淋巴管瘤破裂导致严重腹水：经腹膜后化成功治疗。
Nephrol Dial Transplant. 2004 Apr;19(4):1022-3. doi: 10.1093/ndt/gfh031.
7
Sirolimus and lymphocele formation after kidney transplantation: an immunosuppressive medication as co-factor for a surgical problem?
Nephrol Dial Transplant. 2003 Feb;18(2):448-9. doi: 10.1093/ndt/18.2.448.
8
Late 'spontaneous' kidney graft decapsulation with fluid collection: lymphocele or transudate?晚期“自发性”肾移植包膜剥脱伴积液：淋巴囊肿还是漏出液？
Nephrol Dial Transplant. 1998 May;13(5):1288-91. doi: 10.1093/ndt/13.5.1288.
9
Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C.促炎细胞因子调节淋巴管内皮细胞有丝分裂原血管内皮生长因子-C的表达。
J Biol Chem. 1998 Apr 3;273(14):8413-8. doi: 10.1074/jbc.273.14.8413.
10
Decapsulation of the renal transplant as a mechanism of lymphocele formation.肾移植包膜剥除术作为淋巴管瘤形成的一种机制。
Transplant Proc. 1982 Dec;14(4):741-2.

1例丙型肝炎患者肾移植后使用西罗莫司治疗出现晚期自发性肾被膜剥脱：一种罕见并发症可能的病理生理关联

Late spontaneous decapsulation of the kidney graft in a patient with hepatitis C and treated with sirolimus: possible pathophysiological association in a rare complication.

作者信息

Leal Rita, Pinto Helena, Alves Rui, Figueiredo Arnaldo

机构信息

Department of Nephrology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

出版信息

BMJ Case Rep. 2017 Jan 18;2017:bcr2016218335. doi: 10.1136/bcr-2016-218335.

DOI:10.1136/bcr-2016-218335
PMID:28100577
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5256561/
Abstract

Late decapsulation with fluid collection is a rare complication of renal transplantation with deleterious effects on kidney function. Its physiopathology is unclear but there might be an association with mammalian target of rapamycin (m-TOR) inhibitors, especially in patients with chronic hepatitis C. We report a case of late spontaneous decapsulation 12 years after kidney transplant in a patient infected with hepatitis C under treatment with sirolimus. He underwent marsupialisation of the collection, sirolimus was converted to cyclosporine and hepatitis C treatment was performed with success. This is the first successful case report of late spontaneous decapsulation of the kidney graft in a patient with hepatitis C.

摘要

伴有积液的晚期包膜剥脱是肾移植的一种罕见并发症，对肾功能有有害影响。其病理生理学尚不清楚，但可能与雷帕霉素靶蛋白（m-TOR）抑制剂有关，尤其是在丙型肝炎患者中。我们报告一例肾移植12年后发生晚期自发性包膜剥脱的病例，该患者感染丙型肝炎，正在接受西罗莫司治疗。他接受了积液袋形缝合术，西罗莫司转换为环孢素，丙型肝炎治疗取得成功。这是首例丙型肝炎患者肾移植晚期自发性包膜剥脱成功的病例报告。