Crystallization and preliminary X-ray investigation of a complex between a Fab fragment and its antigen, cyclosporin.

作者信息

Altschuh D, Kocher H P, Quesniaux V F, Schmitter D, Van Regenmortel M H, Thierry J C

机构信息

Laboratoire d'Immunochimie, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France.

出版信息

J Mol Biol. 1989 Sep 5;209(1):177-8. doi: 10.1016/0022-2836(89)90181-2.

Preliminary crystallographic data are given for a complex between the cyclic undecapeptide cyclosporin and the Fab fragment of an anti-cyclosporin monoclonal antibody. Crystals of the complex are orthorhombic with space group P2(1)2(1)2(1) and diffract to 2.7 A resolution. The unit cell dimensions are a = 52.6 A, b = 70.2 A and c = 118.4 A. A native data set to 2.7 A resolution has been collected.