Liu W S, Mu L, Tang X C, Yu Y, Cao X C, Wang X
First Department of Breast Tumors, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjn, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University Ministry of Education, Tianjin 300060, China.
Zhonghua Zhong Liu Za Zhi. 2017 Jan 23;39(1):44-47. doi: 10.3760/cma.j.issn.0253-3766.2017.01.009.
To explore the impact of immediate breast reconstruction on the onset of adjuvant chemotherapy and on the postoperative complications. We retrospectively analyzed the clinical data from female breast cancer patients treated by either modified radical mastectomy with immediate breast reconstruction(IBR) ( =108) or modified radical mastectomy alone(=115), followed by adjuvant chemotherapy at our department between January 2011 and December 2012. There was no significant difference in the overall complication rates between the IBR group and modified radical mastectomy group (49.1% vs. 52.2%, =0.87). However, more secondary surgery was applied in the IBR group than the modified radical mastectomy group (13.0% vs. 1.7%, =0.001). However, the incidence of hematoma in the modified radical mastectomy group was significantly higher than the IBR group (17.4% vs. 4.6%, =0.003). There was a significant difference in the onset of adjuvant chemotherapy between the IBR group and modified radical mastectomy group (21 days vs. 11days, <0.001). Immediate breast reconstruction has no significant impact on the overall complication rate, but increases the incidence of secondary surgery, especially after the initiation of chemotherapy. In addition, it slightly delays adjuvant chemotherapy in the patients.
探讨即刻乳房重建对辅助化疗开始时间及术后并发症的影响。我们回顾性分析了2011年1月至2012年12月期间在我科接受治疗的女性乳腺癌患者的临床资料，这些患者分别接受了改良根治术联合即刻乳房重建（IBR）（n = 108）或单纯改良根治术（n = 115），随后进行辅助化疗。IBR组和改良根治术组的总体并发症发生率无显著差异（49.1%对52.2%，P = 0.87）。然而，IBR组比改良根治术组应用了更多的二次手术（13.0%对1.7%，P = 0.001）。但是，改良根治术组的血肿发生率显著高于IBR组（17.4%对4.6%，P = 0.003）。IBR组和改良根治术组在辅助化疗开始时间上存在显著差异（21天对11天，P < 0.001）。即刻乳房重建对总体并发症发生率无显著影响，但会增加二次手术的发生率，尤其是在化疗开始后。此外，它会使患者的辅助化疗稍有延迟。
