Figuerola-Tejerina A, Bustamante E, Tamayo E, Mestres C A, Bustamante-Munguira J
Department of Prevention & Control of Infection, Hospital Universitario de La Princesa, Madrid, Spain.
Department of Critical Care, Hospital Can Misses, Balearic Island, Spain.
Eur J Clin Microbiol Infect Dis. 2017 Jun;36(6):1041-1046. doi: 10.1007/s10096-016-2889-0. Epub 2017 Jan 19.
Surgical site infection (SSI) is a major infectious complication that increases mortality, morbidity, and healthcare costs. There are scores attempting to classify patients for calculating SSI risk. Our objectives were to validate the Australian Clinical Risk Index (ACRI) in a European population after cardiac surgery, comparing it against the National Nosocomial Infections Surveillance-derived risk index (NNIS) and analyzing the predictive power of ACRI for SSI in valvular patients. All the patients that who underwent cardiac surgery in a tertiary university hospital between 2011 and 2015 were analyzed. The patients were divided into valvular and coronary groups, excluding mixed patients. The ACRI score was validated in both groups and its ability to predict SSI was compared to the NNIS risk index. We analyzed 1,657 procedures. In the valvular patient group (n: 1119), a correlation between the ACRI score and SSI development (p < 0.05) was found; there was no such correlation with the NNIS index. The area under the receiver-operating characteristic curve (AUC) was 0.64 (confidence interval [CI] 95%, 0.5-0.7) for ACRI and 0.62 (95% CI, 0.5-0.7) for NNIS. In the coronary group (n: 281), there was a correlation between ACRI and SSI but no between NNIS and SSI. The ACRI AUC was 0.70 (95% CI, 0.5-0.8) and the NNIS AUC was 0.60 (95% CI, 0.4-0.7). The ACRI score has insufficient predictive power, although it predicts SSI development better than the NNIS index, fundamentally in coronary artery bypass grafting (CABG). Further studies analyzing determining factors are needed.
手术部位感染(SSI)是一种主要的感染性并发症,会增加死亡率、发病率和医疗成本。有多种评分方法试图对患者进行分类以计算SSI风险。我们的目标是在欧洲心脏手术人群中验证澳大利亚临床风险指数(ACRI),将其与美国国家医院感染监测系统得出的风险指数(NNIS)进行比较,并分析ACRI对瓣膜病患者SSI的预测能力。对2011年至2015年间在一所三级大学医院接受心脏手术的所有患者进行了分析。患者分为瓣膜病组和冠心病组,不包括混合型患者。在两组中对ACRI评分进行了验证,并将其预测SSI的能力与NNIS风险指数进行了比较。我们分析了1657例手术。在瓣膜病患者组(n = 1119)中,发现ACRI评分与SSI发生之间存在相关性(p < 0.05);与NNIS指数无此相关性。ACRI的受试者操作特征曲线下面积(AUC)为0.64(95%置信区间[CI],0.5 - 0.7),NNIS为0.62(95%CI,0.5 - 0.7)。在冠心病组(n = 281)中,ACRI与SSI之间存在相关性,但NNIS与SSI之间无相关性。ACRI的AUC为0.70(95%CI,0.5 - 0.8),NNIS的AUC为0.60(95%CI,0.4 - 0.7)。ACRI评分的预测能力不足,尽管它在预测SSI发生方面比NNIS指数更好,尤其是在冠状动脉旁路移植术(CABG)中。需要进一步研究分析决定因素。