Tanaka M, Dohi S
Masui. 1989 Aug;38(8):1083-91.
One of the most common problems in emergency anesthesia for cerebral aneurysm surgery is clinically significant ECG abnormalities. We had a 58 year old patient with severe subarachnoid hemorrhage and diffuse lung edema leading to fatal outcome probably due to catecholamine myocardial injury. During the operative intervention with enflurane and oxygen anesthesia, ST elevation on ECG suddenly appeared and heart failure developed in this patient. Intraoperative ECG suggested the development of acute myocardial infarction of the anterior and inferior wall, but echocardiography revealed a discrepant result; the wall motion abnormality was confirmed in the apex only. The serum CPK in this patient increased a little over the normal limit perioperatively. Overall results suggested that a cause of this patient's death was myocardial injury due to the excessive release of catecholamine. Therefore, we urge the need of through cardiac examinations as well as the administration of preventive drugs for catecholamine myocardial injury in the perioperative management of patients with severe subarachnoid hemorrhage.
脑动脉瘤手术急诊麻醉中最常见的问题之一是具有临床意义的心电图异常。我们有一位58岁的患者,患有严重蛛网膜下腔出血和弥漫性肺水肿,可能由于儿茶酚胺心肌损伤导致了致命后果。在使用恩氟烷和氧气麻醉进行手术干预期间,该患者心电图突然出现ST段抬高并发生心力衰竭。术中心电图提示前壁和下壁急性心肌梗死,但超声心动图显示结果不一致;仅在心尖部确认有室壁运动异常。该患者围手术期血清肌酸磷酸激酶略高于正常上限。总体结果表明,该患者死亡原因是儿茶酚胺过度释放导致的心肌损伤。因此,我们敦促在严重蛛网膜下腔出血患者的围手术期管理中,需要进行全面的心脏检查以及给予预防儿茶酚胺心肌损伤的药物。