Nakamura N, Kojima H, Nagashima K, Aida T, Kaneko S, Kitaoka K, Abe H
Dept. of Laboratory Technology, College of Medical Technology.
Gan No Rinsho. 1989 Sep;35(11):1313-23.
C-T scan findings in glioma and brain tissue after irradiation were histopathologically analyzed with the post-mortem examination of 4 patients. High density of contrast enhancement observed in gliomas mainly corresponded to proliferation of irregular blood vessels and hypodensity reflected less cellular area or necrotic foci in the tumor tissue. A mottled lesion with high density margin in C-T of radionecrosis of the brain tissue observed in a non-glioma patient was formed by coagulation necrosis showing marked proliferation of telangiectatic blood vessels in periphery of lesion and acellular area in the center. It is occasionally impossible to differentiate the findings between delayed radionecrosis of brain and recurrence of glioma using the C-T criteria alone.
对4例患者进行尸检,对胶质瘤和放疗后脑组织的CT扫描结果进行组织病理学分析。胶质瘤中观察到的高密度对比增强主要对应于不规则血管的增生,低密度反映肿瘤组织中细胞较少的区域或坏死灶。在一名非胶质瘤患者的脑组织放射性坏死的CT中观察到的边缘高密度的斑驳病变是由凝固性坏死形成的,病变周边显示明显的扩张性血管增生,中心为无细胞区。仅使用CT标准,有时无法区分脑迟发性放射性坏死和胶质瘤复发的表现。