College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China.
Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China.
Talanta. 2017 Mar 1;164:427-431. doi: 10.1016/j.talanta.2016.07.028. Epub 2016 Jul 12.
Lanthanide coordination polymers (LCPs) have emerged as fascinating materials because of their specific structure and properties. In this work, utilizing hydrosoluble biomolecule of guanosine-5'-monophosphate (GMP) as bridging linker, lanthanide terbium ions (Tb) as metal nodes, and silver ions (Ag) as sensitizers, we synthesized a pH responsive luminescent lanthanide CP probe of Tb/GMP/Ag. The probe possesses high luminescence due to the sensitization of Ag; While in alkaline solutions, Ag in Tb/GMP/Ag immediately binds to OH, forming AgO precipitation and resulting in a distinct fluorescence quenching of Tb/GMP/Ag. This probe displays high selectivity for OH and a broader pH detection range of 7.5-13.0. In addition, based on the high anti-interference ability in serum, we applied Tb/GMP/Ag to measure pH in undiluted human serum samples, yielding satisfactory results.
镧系配位聚合物（LCPs）因其特殊的结构和性质而成为引人注目的材料。在这项工作中，我们利用水溶性生物分子鸟苷-5'-单磷酸（GMP）作为桥连配体，镧系元素铽离子（Tb）作为金属节点，以及银离子（Ag）作为敏化剂，合成了一种 pH 响应发光镧系 CP 探针 Tb/GMP/Ag。该探针由于 Ag 的敏化作用具有高发光性；而在碱性溶液中，Tb/GMP/Ag 中的 Ag 立即与 OH 结合，形成 AgO 沉淀，导致 Tb/GMP/Ag 的荧光显著猝灭。该探针对 OH 具有高选择性，检测 pH 的范围较宽，为 7.5-13.0。此外，基于在血清中具有高抗干扰能力，我们将 Tb/GMP/Ag 应用于未经稀释的人血清样品中 pH 的测定，得到了令人满意的结果。
