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J Biomed Inform. 2015 Dec;58 Suppl(0):S120-S127. doi: 10.1016/j.jbi.2015.06.030. Epub 2015 Jul 22.
2
OrderRex: clinical order decision support and outcome predictions by data-mining electronic medical records.OrderRex:通过数据挖掘电子病历实现临床医嘱决策支持与结果预测。
J Am Med Inform Assoc. 2016 Mar;23(2):339-48. doi: 10.1093/jamia/ocv091. Epub 2015 Jul 21.
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Detection of Drug-Drug Interactions Inducing Acute Kidney Injury by Electronic Health Records Mining.通过电子健康记录挖掘检测导致急性肾损伤的药物相互作用
Drug Saf. 2015 Sep;38(9):799-809. doi: 10.1007/s40264-015-0311-y.
4
Extracting Concepts Related to Homelessness from the Free Text of VA Electronic Medical Records.从退伍军人事务部电子病历的自由文本中提取与无家可归相关的概念。
AMIA Annu Symp Proc. 2014 Nov 14;2014:589-98. eCollection 2014.
5
Development and validation of a classification approach for extracting severity automatically from electronic health records.一种用于从电子健康记录中自动提取严重程度的分类方法的开发与验证。
J Biomed Semantics. 2015 Apr 6;6:14. doi: 10.1186/s13326-015-0010-8. eCollection 2015.
6
Validation of electronic health record phenotyping of bipolar disorder cases and controls.双相情感障碍病例与对照的电子健康记录表型验证。
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7
Detecting disease outbreaks using a combined Bayesian network and particle filter approach.使用贝叶斯网络和粒子滤波器相结合的方法检测疾病爆发。
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8
Automatic identification of methotrexate-induced liver toxicity in patients with rheumatoid arthritis from the electronic medical record.从电子病历中自动识别类风湿性关节炎患者甲氨蝶呤诱导的肝毒性。
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9
First in line: prioritizing receipt of Social Security disability benefits based on likelihood of death during adjudication.排在首位:根据裁决期间的死亡可能性优先获得社会保障残疾福利。
Med Care. 2014 Nov;52(11):944-50. doi: 10.1097/MLR.0000000000000204.
10
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自动健康记录审查,以帮助确定重症社会保障残疾申请人的优先顺序。

Automatic health record review to help prioritize gravely ill Social Security disability applicants.

作者信息

Abbott Kenneth, Ho Yen-Yi, Erickson Jennifer

机构信息

Minnesota Disability Determination Services, Saint Paul, Minnesota, USA.

Department of Statistics, College of Arts and Sciences, University of South Carolina, Columbia, SC, USA.

出版信息

J Am Med Inform Assoc. 2017 Jul 1;24(4):709-716. doi: 10.1093/jamia/ocw159.

DOI:10.1093/jamia/ocw159
PMID:28108546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7651957/
Abstract

OBJECTIVE

Every year, thousands of patients die waiting for disability benefits from the Social Security Administration. Some qualify for expedited service under the Compassionate Allowance (CAL) initiative, but CAL software focuses exclusively on information from a single form field. This paper describes the development of a supplemental process for identifying some overlooked but gravely ill applicants, through automatic annotation of health records accompanying new claims. We explore improved prioritization instead of fully autonomous claims approval.

MATERIALS AND METHODS

We developed a sample of claims containing medical records at the moment of arrival in a single office. A series of tools annotated both patient records and public Web page descriptions of CAL medical conditions. We trained random forests to identify CAL patients and validated each model with 10-fold cross validation.

RESULTS

Our main model, a general CAL classifier, had an area under the receiver operating characteristic curve of 0.915. Combining this classifier with existing software improved sensitivity from 0.960 to 0.994, detecting every deceased patient, but reducing positive predictive value to 0.216.

DISCUSSION

True positive CAL identification is a priority, given CAL patient mortality. Mere prioritization of the false positives would not create a meaningful burden in terms of manual review. Death certificate data suggest the presence of truly ill patients among putative false positives.

CONCLUSION

To a limited extent, it is possible to identify gravely ill Social Security disability applicants by analyzing annotations of unstructured electronic health records, and the level of identification is sufficient to be useful in prioritizing case reviews.

摘要

目的

每年都有成千上万的患者在等待社会保障管理局的残疾福利金时死亡。一些患者符合“同情性津贴(CAL)”计划下的加急服务条件,但CAL软件仅专注于单个表单字段中的信息。本文描述了一种补充流程的开发,该流程通过对新申请附带的健康记录进行自动标注,来识别一些被忽视但病情严重的申请人。我们探索改进优先级排序,而非完全自主进行理赔审批。

材料与方法

我们创建了一个在单个办公室收到申请时包含医疗记录的样本。一系列工具对患者记录以及CAL医疗状况的公共网页描述进行了标注。我们训练随机森林来识别CAL患者,并通过10折交叉验证对每个模型进行验证。

结果

我们的主要模型,即通用CAL分类器,在接收者操作特征曲线下的面积为0.915。将此分类器与现有软件相结合,灵敏度从0.960提高到了0.994,能检测到每一位死亡患者,但阳性预测值降至0.216。

讨论

鉴于CAL患者的死亡率,准确识别真阳性患者是当务之急。仅对假阳性进行优先级排序在人工审核方面不会造成有意义的负担。死亡证明数据表明在推定的假阳性患者中存在真正患病的患者。

结论

在一定程度上,通过分析非结构化电子健康记录的标注来识别病情严重的社会保障残疾申请人是可行的,且识别水平足以在确定案件审核优先级方面发挥作用。