The Th2 gene cluster unraveled: role of RHS6.
作者信息
Flayer C H, Haczku A
机构信息
Pulmonary, Critical Care and Sleep Medicine, Translational Lung Biology Center, University of California, Davis, Davis, CA, USA.
出版信息
Allergy. 2017 May;72(5):679-681. doi: 10.1111/all.13130.
Abstract
摘要
相似文献
1
The Th2 gene cluster unraveled: role of RHS6.Th2基因簇解析：RHS6的作用
Allergy. 2017 May;72(5):679-681. doi: 10.1111/all.13130.
2
RHS6 coordinately regulates the Th2 cytokine genes by recruiting GATA3, SATB1, and IRF4.RHS6 通过募集 GATA3、SATB1 和 IRF4 来协调调控 Th2 细胞因子基因。
Allergy. 2017 May;72(5):772-782. doi: 10.1111/all.13078. Epub 2016 Nov 23.
3
RHS6-mediated chromosomal looping and nuclear substructure binding is required for Th2 cytokine gene expression.RHS6 介导的染色体环化和核亚结构结合是 Th2 细胞因子基因表达所必需的。
Biochim Biophys Acta Gene Regul Mech. 2017 Mar;1860(3):383-391. doi: 10.1016/j.bbagrm.2017.01.008. Epub 2017 Jan 27.
4
Replication initiation from a novel origin identified in the Th2 cytokine cluster locus requires a distant conserved noncoding sequence.从Th2细胞因子簇基因座中鉴定出的一个新起点进行复制起始需要一个远距离保守非编码序列。
J Immunol. 2006 May 1;176(9):5446-54. doi: 10.4049/jimmunol.176.9.5446.
5
Characterization and profiling of immunomodulatory genes in resident mesenchymal stem cells reflect the Th1-Th17/Th2 imbalance of psoriasis.常驻间充质干细胞中免疫调节基因的表征与分析反映了银屑病的Th1-Th17/Th2失衡。
Arch Dermatol Res. 2014 Dec;306(10):915-20. doi: 10.1007/s00403-014-1493-3. Epub 2014 Aug 27.
6
[Study on the correlation of the effect of entecavir on Th1/Th2 cytokines level in the treatment of chronic hepatitis].恩替卡韦治疗慢性乙型肝炎对Th1/Th2细胞因子水平影响的相关性研究
Zhonghua Gan Zang Bing Za Zhi. 2017 Aug 20;25(8):606-611. doi: 10.3760/cma.j.issn.1007-3418.2017.08.010.
7
Expression patterns of Th1 and Th2 cytokine genes in childhood idiopathic thrombocytopenic purpura (ITP) at presentation and their modulation by intravenous immunoglobulin G (IVIg) treatment: their role in prognosis.儿童特发性血小板减少性紫癜（ITP）初诊时Th1和Th2细胞因子基因的表达模式及其受静脉注射免疫球蛋白G（IVIg）治疗的调节：它们在预后中的作用
Blood. 2002 Sep 1;100(5):1774-9.
8
[Cytokine gene expression in Th1 and Th2: its molecular mechanism and clinical implication].
Nihon Rinsho. 1997 Jun;55(6):1431-7.
9
IL-1 family members IL-18 and IL-33 upregulate the inflammatory potential of differentiated human Th1 and Th2 cultures.白细胞介素-1 家族成员白细胞介素-18 和白细胞介素-33 上调分化的人 Th1 和 Th2 培养物的炎症潜能。
J Immunol. 2012 Nov 1;189(9):4331-7. doi: 10.4049/jimmunol.1103685. Epub 2012 Oct 1.
10
Interleukin-18 regulates both Th1 and Th2 responses.白细胞介素-18调节Th1和Th2反应。
Annu Rev Immunol. 2001;19:423-74. doi: 10.1146/annurev.immunol.19.1.423.
引用本文的文献
1
Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma.用于过敏性疾病和哮喘诊断及治疗反应预测的生物标志物。
Allergy. 2020 Dec;75(12):3039-3068. doi: 10.1111/all.14582. Epub 2020 Sep 30.
2
Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care.未来研究趋势旨在深入了解过敏疾病的发病机制，以改善患者的护理。
Allergy. 2019 Dec;74(12):2293-2311. doi: 10.1111/all.13851. Epub 2019 Jun 4.
3
Dendritic cells, engineered to overexpress 25-hydroxyvitamin D 1α-hydroxylase and pulsed with a myelin antigen, provide myelin-specific suppression of ongoing experimental allergic encephalomyelitis.经过基因工程改造以过表达25-羟基维生素D 1α-羟化酶并与髓磷脂抗原脉冲处理的树突状细胞，可对正在进行的实验性自身免疫性脑脊髓炎提供髓磷脂特异性抑制作用。
FASEB J. 2017 Jul;31(7):2996-3006. doi: 10.1096/fj.201601243R. Epub 2017 Mar 31.
本文引用的文献
1
RHS6 coordinately regulates the Th2 cytokine genes by recruiting GATA3, SATB1, and IRF4.RHS6 通过募集 GATA3、SATB1 和 IRF4 来协调调控 Th2 细胞因子基因。
Allergy. 2017 May;72(5):772-782. doi: 10.1111/all.13078. Epub 2016 Nov 23.
2
An Interleukin 13 Polymorphism Is Associated with Symptom Severity in Adult Subjects with Ever Asthma.白细胞介素13基因多态性与成年曾患哮喘患者的症状严重程度相关。
PLoS One. 2016 Mar 17;11(3):e0151292. doi: 10.1371/journal.pone.0151292. eCollection 2016.
3
Transcription Factors Oct-1 and GATA-3 Cooperatively Regulate Th2 Cytokine Gene Expression via the RHS5 within the Th2 Locus Control Region.转录因子Oct-1和GATA-3通过Th2基因座控制区内的RHS5协同调节Th2细胞因子基因表达。
PLoS One. 2016 Feb 3;11(2):e0148576. doi: 10.1371/journal.pone.0148576. eCollection 2016.
4
Effector T cell differentiation: are master regulators of effector T cells still the masters?效应T细胞分化：效应T细胞的主调控因子还是主宰者吗？
Curr Opin Immunol. 2015 Dec;37:6-10. doi: 10.1016/j.coi.2015.08.001. Epub 2015 Aug 27.
5
Group 2 innate lymphoid cells mediate ozone-induced airway inflammation and hyperresponsiveness in mice.第2组固有淋巴细胞介导臭氧诱导的小鼠气道炎症和高反应性。
J Allergy Clin Immunol. 2016 Feb;137(2):571-8. doi: 10.1016/j.jaci.2015.06.037. Epub 2015 Aug 15.
6
Asthma phenotyping: a necessity for improved therapeutic precision and new targeted therapies.哮喘表型分析：提高治疗精确性和新型靶向治疗的必要手段。
J Intern Med. 2016 Feb;279(2):192-204. doi: 10.1111/joim.12382. Epub 2015 Jun 15.
7
EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders.EAACI IG 生物制剂工作组关于在过敏性疾病中使用生物制剂的论文。
Allergy. 2015 Jul;70(7):727-54. doi: 10.1111/all.12616. Epub 2015 Apr 24.
8
Fine-mapping of IgE-associated loci 1q23, 5q31, and 12q13 using 1000 Genomes Project data.利用 1000 基因组计划数据对 IgE 相关基因座 1q23、5q31 和 12q13 进行精细定位。
Allergy. 2014 Aug;69(8):1077-84. doi: 10.1111/all.12431. Epub 2014 Jun 14.
9
A polymorphism in the TH 2 locus control region is associated with changes in DNA methylation and gene expression.TH2 基因座控制区的多态性与 DNA 甲基化和基因表达的变化有关。
Allergy. 2014 Sep;69(9):1171-80. doi: 10.1111/all.12450. Epub 2014 Jul 14.
10
Understanding the regulatory and transcriptional complexity of the genome through structure.通过结构来理解基因组的调控和转录复杂性。
Genome Res. 2013 Jul;23(7):1081-8. doi: 10.1101/gr.156612.113.
Zotero 插件