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[梗死相关动脉冠状动脉血管成形术(PTCA)在既往心肌梗死患者中的应用价值——通过负荷铊扫描对血管成形术前和术后梗死区域的随访]

[Usefulness of coronary angioplasty (PTCA) of the infarct-related artery in patients with prior myocardial infarction--follow up of infarct zone pre- and post-angioplasty by stress thallium scan].

作者信息

Chiba H, Nishimura T, Uehara T, Hayashida K, Mitani I, Matsuo T, Sumiyoshi T, Haze K

出版信息

Kaku Igaku. 1989 Jul;26(7):835-44.

PMID:2810902
Abstract

We studied the efficacy of coronary angioplasty (PTCA) of the infarct-related artery in 29 patients with prior myocardial infarction by stress thallium scan. Twenty-seven patients had anterior myocardial infarction (single LAD disease), one had inferior (single RCA disease) and one had posterior (single LCX disease). According to the stress-redistribution thallium scintigraphic finding before PTCA, the patients were classified in 4 groups; (A): three patients with complete redistribution. (B): fourteen patients with incomplete redistribution. (C): seven patients with partial redistribution. (D): five patients with no redistribution. After PTCA, the parameters of residual ischemia in the infarct area (% RD and Thallium ischemic score = TIS) were improved significantly but those of infarct size (RD% uptake and Defect Score = DS) were improved slightly in group A. In group B and C, % RD, TIS, RD% uptake and DS were all improved significantly. In group D, TIS was improved slightly and DS was improved slowly 3 months after PTCA. Group A had high probability of viable muscle and group D had high probability of scar at the infarct zone. Group B and C showed intermediate type between group A and D. The change of infarct area after PTCA was variable in 4 groups but both residual ischemia and infarct size decreased in all groups. Thus, PTCA of infarct-related coronary artery is useful even in the patients with prior myocardial infarction.

摘要

我们通过负荷铊扫描研究了29例既往有心肌梗死患者梗死相关动脉冠状动脉成形术(PTCA)的疗效。27例患者为前壁心肌梗死(单支左前降支病变),1例为下壁(单支右冠状动脉病变),1例为后壁(单支左旋支病变)。根据PTCA前负荷-再分布铊闪烁显像结果,将患者分为4组:(A):3例完全再分布。(B):14例不完全再分布。(C):7例部分再分布。(D):5例无再分布。PTCA后,梗死区域残余缺血参数(%RD和铊缺血评分=TIS)在A组显著改善,但梗死面积参数(RD%摄取和缺损评分=DS)改善轻微。在B组和C组,%RD、TIS、RD%摄取和DS均显著改善。在D组,PTCA后3个月TIS改善轻微,DS改善缓慢。A组梗死区域存活心肌可能性高,D组梗死区域瘢痕可能性高。B组和C组显示介于A组和D组之间的中间类型。PTCA后4组梗死面积变化各异,但所有组残余缺血和梗死面积均减小。因此,梗死相关冠状动脉PTCA即使在既往有心肌梗死的患者中也有用。

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