Ramieri Valerio, Basile Emanuela, Bosco Giulio, Caresta Elena, Papoff Paola, Cascone Piero
Dipartimento di Scienze Odontostomatologiche e Maxillo Facciale (Head: Prof. Ersilia Barbato), "Sapienza" Università di Roma, Italy.
Dipartimento di Scienze Odontostomatologiche e Maxillo Facciale (Head: Prof. Ersilia Barbato), "Sapienza" Università di Roma, Italy.
J Craniomaxillofac Surg. 2017 Mar;45(3):377-380. doi: 10.1016/j.jcms.2016.12.007. Epub 2016 Dec 18.
Newborns with Pierre Robin sequence (PRS) and syndromic micrognathia show microgenia and glossoptosis, which cause reduction of the airway and breathing difficulty from birth. Our goal is to analyze quantitative and qualitative volumetric changes before and after fast and early mandibular osteodistraction (FEMOD) and to compare radiological data.
The sample was composed of 4 patients, who satisfied inclusion criteria for completeness of data. Computed tomography pre- and post-operation were performed, then a volumetric assessment was made with Dolphin Imaging. Polysomnography was performed before and after FEMOD.
Pre- and post-operative CT scan data were compared. The analysis of all three sections showed a significant increase of volumetric parameters. The retroglossal volume average increase was 346%, and the retropalatal volume average increase was 169%. These data matched the improvement recorded by polysomnography.
The data confirm FEMOD as an efficient treatment to improve airways and breathing problem in patients affected by Pierre Robin sequence and syndromic micrognathia. The three-dimensional volume rendering could be a useful method to evaluate and quantify the increase in airways volume.
患有皮埃尔·罗宾序列征（PRS）和综合征性小颌畸形的新生儿表现出小颏和舌后坠，这会导致气道狭窄并自出生起就出现呼吸困难。我们的目标是分析快速早期下颌骨牵张成骨术（FEMOD）前后的定量和定性容积变化，并比较放射学数据。
样本由4名满足数据完整性纳入标准的患者组成。在手术前后进行计算机断层扫描，然后使用Dolphin Imaging进行容积评估。在FEMOD前后进行多导睡眠图检查。
比较手术前后的CT扫描数据。对所有三个层面的分析均显示容积参数显著增加。舌后间隙平均容积增加346%，腭后间隙平均容积增加169%。这些数据与多导睡眠图记录的改善情况相符。
数据证实FEMOD是改善受皮埃尔·罗宾序列征和综合征性小颌畸形影响患者气道和呼吸问题的有效治疗方法。三维容积重建可能是评估和量化气道容积增加的有用方法。
