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儿童原发性间质性肝肿瘤

Primary mesenchymal liver tumors of childhood.

作者信息

Saeed Omer, Saxena Romil

机构信息

Indiana University School of Medicine, United States.

Indiana University School of Medicine, United States.

出版信息

Semin Diagn Pathol. 2017 Mar;34(2):201-207. doi: 10.1053/j.semdp.2016.12.016. Epub 2016 Dec 23.

Abstract

Primary mesenchymal tumors of the liver represent a significant proportion of liver tumors among neonates, infants and young children. They may be discovered incidentally or present with an alarmingly large, rapidly growing abdominal mass. One third of pediatric liver tumors are benign with hemangioma and mesenchymal hamartoma being the commonest in that order. Infantile hemangioendothelioma and mesenchymal hamartoma represent the commonest liver tumors among neonates and infants. Mesenchymal hamartoma may even present in utero. A biopsy is often required for definitive diagnosis due to considerable overlap in clinical presentation and radiological findings amongst these tumors, as well as with hepatoblastoma.

摘要

肝脏原发性间叶性肿瘤在新生儿、婴儿和幼儿的肝脏肿瘤中占相当大的比例。它们可能是偶然发现的,也可能表现为令人担忧的巨大、快速生长的腹部肿块。三分之一的儿童肝脏肿瘤是良性的,血管瘤和间叶性错构瘤依次是最常见的。婴儿血管内皮瘤和间叶性错构瘤是新生儿和婴儿中最常见的肝脏肿瘤。间叶性错构瘤甚至可能在子宫内出现。由于这些肿瘤以及肝母细胞瘤在临床表现和影像学检查结果上有相当大的重叠,因此往往需要进行活检以明确诊断。

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