日本缓慢进展型1型糖尿病患者中HLA单倍型与体重指数变化的关系。
Relationship between HLA haplotype and BMI change in Japanese slowly progressive type 1 diabetes patients.
作者信息
Hoshina Sari, Miura Junnosuke, Uchigata Yasuko
机构信息
Diabetes Center, Tokyo Women's Medical University School of Medicine, Japan.
Diabetes Center, Tokyo Women's Medical University School of Medicine, Japan.
出版信息
Diabetes Res Clin Pract. 2017 Feb;124:81-83. doi: 10.1016/j.diabres.2016.12.006. Epub 2016 Dec 28.
We investigated the association between susceptible HLA and BMI change rate from diagnosis of diabetes to diagnosis of slowly progressive type 1 diabetes in Japanese diabetic patients. Subjects with the HLA DRB104:05-DQB104:01 haplotype were more likely to show weight loss than those without. This HLA haplotype might affect weight loss.
我们调查了日本糖尿病患者中，易感性HLA与从糖尿病诊断到缓慢进展型1型糖尿病诊断期间体重指数变化率之间的关联。携带HLA DRB104:05-DQB104:01单倍型的受试者比未携带该单倍型的受试者更易出现体重减轻。这种HLA单倍型可能会影响体重减轻。
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