Strempel I, Grüber A, Bittner K
Univers. Augenklinik Marburg/Lahn.
Klin Monbl Augenheilkd. 1989 Sep;195(3):141-4. doi: 10.1055/s-2008-1046425.
Fifty-three patients with severe renal disease and/or kidney transplants underwent full ophthalmological examinations, including tear breakup time, Schirmer's test, and impression cytology of the conjunctivae. Although only some 50% of the patients complained of typical dry-eye symptoms, pathologic changes of the outer eye were found in almost 70%. Tear break-up times and Schirmer's test values were greatly reduced. Morphological changes of the conjunctiva were found in almost all the patients; in 50% of these cases the changes were moderate to severe.