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与临床测量相比,对几何参数化髋关节撞击风险的三维评估。

Three-dimensional assessment of impingement risk in geometrically parameterised hips compared with clinical measures.

作者信息

Cooper Robert J, Mengoni Marlène, Groves Dawn, Williams Sophie, Bankes Marcus J K, Robinson Philip, Jones Alison C

机构信息

Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds, LS2 9JT, UK.

Guy's Hospital, Great Maze Pond, London, SE1 9RT, UK.

出版信息

Int J Numer Method Biomed Eng. 2017 Nov;33(11). doi: 10.1002/cnm.2867. Epub 2017 Apr 5.

Abstract

Abnormal bony morphology is a factor implicated in hip joint soft tissue damage and an increased lifetime risk of osteoarthritis. Standard 2-dimensional radiographic measurements for diagnosis of hip deformities, such as cam deformities on the femoral neck, do not capture the full joint geometry and are not indicative of symptomatic damage. In this study, a 3-dimensional geometric parameterisation system was developed to capture key variations in the femur and acetabulum of subjects with clinically diagnosed cam deformity. The parameterisation was performed for computed tomography scans of 20 patients (10 female and 10 male). Novel quantitative measures of cam deformity were taken and used to assess differences in morphological deformities between males and females. The parametric surfaces matched the more detailed, segmented hip bone geometry with low fitting error. The quantitative severity measures captured both the size and the position of cams and distinguished between cam and control femurs. The precision of the measures was sufficient to identify differences between subjects that could not be seen with the sole use of 2-dimensional imaging. In particular, cams were found to be more superiorly located in males than in females. As well as providing a means to distinguish between subjects more clearly, the new geometric hip parameterisation facilitates the flexible and rapid generation of a range of realistic hip geometries including cams. When combined with material property models, these stratified cam shapes can be used for further assessment of the effect of the geometric variation under impingement conditions.

摘要

异常的骨骼形态是髋关节软组织损伤和骨关节炎终生风险增加的一个相关因素。用于诊断髋关节畸形(如股骨颈凸轮畸形)的标准二维放射学测量方法无法捕捉整个关节的几何形状,也不能指示有症状的损伤。在本研究中,开发了一种三维几何参数化系统,以捕捉临床诊断为凸轮畸形的受试者股骨和髋臼的关键变化。对20名患者(10名女性和10名男性)的计算机断层扫描进行了参数化。采用了新的凸轮畸形定量测量方法,并用于评估男性和女性之间形态畸形的差异。参数化表面以低拟合误差匹配了更详细的、分割后的髋骨几何形状。定量严重程度测量方法捕捉了凸轮的大小和位置,并区分了凸轮股骨和对照股骨。这些测量方法的精度足以识别仅使用二维成像无法看到的受试者之间的差异。特别是,发现凸轮在男性中的位置比女性更高。新的髋部几何参数化不仅提供了一种更清晰地区分受试者的方法,还便于灵活快速地生成一系列包括凸轮在内的逼真髋部几何形状。当与材料特性模型结合时,这些分层的凸轮形状可用于进一步评估撞击条件下几何变化的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0399/5724697/12056b9b23b5/CNM-33-na-g001.jpg

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