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[恶性骨肿瘤和骨转移瘤病理性股骨骨折的处理]

[Managing pathologic femoral fractures in malignant bone tumors and skeletal metastases].

作者信息

Kurock W, Sennerich T, von Issendorff W D

机构信息

Klinik und Poliklinik für Unfallchirurgie, Universitätsklinikum Mainz.

出版信息

Langenbecks Arch Chir. 1989;374(5):291-8. doi: 10.1007/BF01261472.

Abstract

In adults pathological fractures of the femur are mostly caused by skeletal metastases. In our own collective of femoral fractures 58 were caused by skeletal metastases and five by multiple myeloma. Average age was 59.8 years, women prevailed. In most of the metastatic fractures breast cancer was found to be the primary tumour. In all cases fracture stabilization as a palliative measure was the only possible therapy. Two patients could not be operated on because of other vital problems. In femoral neck fractures resection and endoprosthesis was the operative measure of choice. The pertrochanteric and subtrochanteric fractures were mostly treated by composites of cement and the 95 degrees condylar-plate. Also in shaft fractures cement-implant composites were performed with straight plates. Rarely, intramedullary nailing was done. Exercising stability could always be achieved, weight-bearing stability in most of the cases. The mean survival time was 7.2 months regarding 43 patients with well documented course. Six patients are controlled regularly, the operative treatment was done on an average 16 months before.

摘要

在成年人中,股骨病理性骨折大多由骨转移引起。在我们自己收集的股骨骨折病例中,58例由骨转移引起,5例由多发性骨髓瘤引起。平均年龄为59.8岁,女性居多。在大多数转移性骨折病例中,发现原发性肿瘤为乳腺癌。在所有病例中,骨折固定作为一种姑息性措施是唯一可行的治疗方法。两名患者因其他重要问题无法进行手术。对于股骨颈骨折,切除和植入假体是首选的手术措施。转子间和转子下骨折大多采用骨水泥与95度髁钢板的组合进行治疗。对于股骨干骨折,也采用骨水泥植入物与直板的组合。很少进行髓内钉固定。总能实现锻炼稳定性,在大多数情况下能实现负重稳定性。在43例病程记录良好的患者中,平均生存时间为7.2个月。6例患者接受定期复查,手术治疗平均在16个月前进行。

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