Suppr超能文献

[利用针对肠道β1微管蛋白抗原的131I抗体对人结肠癌进行实验性可视化研究]

[Experimental visualization of human colon cancer using 131I-antibodies to intestinal beta 1 MA antigen].

作者信息

Fidler L M, Aleksander S K, Mit'kov V B, Pugachev K K, Lukin Iu V, Avdeev G I

出版信息

Med Radiol (Mosk). 1989 Oct;34(10):53-7.

PMID:2811630
Abstract

131I-antibodies to human beta 1 colonic antigen was administered i.v. to nude mice with transplanted human colon carcinoma. Injections were followed by mouse whole-body investigation with the help of gamma-camera and scanner. The distribution of radioactivity in murine tissues was investigated with a gamma-counter. Sharp images of tumor were obtained with the help of the gamma-camera and scanner. The results of visualization were in accord with radioimmunometric data. A conclusion was made of effective visualization of human colon carcinoma transplanted to nude mice using iodinated antibodies to specific beta 1 MA epithelial colonic antigen.

摘要

将抗人β1结肠抗原的131I抗体静脉注射给移植了人结肠癌的裸鼠。注射后,借助γ相机和扫描仪对小鼠进行全身检查。用γ计数器研究放射性在鼠组织中的分布。借助γ相机和扫描仪获得了肿瘤的清晰图像。可视化结果与放射免疫测定数据一致。得出结论,使用针对特定β1 MA结肠上皮抗原的碘化抗体可有效可视化移植到裸鼠体内的人结肠癌。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验