Pasqualetti P, Casale R, Colantonio D
Medicina (Firenze). 1989 Apr-Jun;9(2):182-4.
The reliability of the mathematical model for calculating survival proposed by Merlini, Waldenstrom e Jayakar (1980) was tested in a group of 80 patients with multiple myeloma. The observed and calculated survivals were compared using univariate regression analysis. The results show that a significant (p less than 0.001) relationship between observed and calculated survival exists in the study patient group. These observations confirm that this useful and reliable clinical staging system can be a basis for individualization of a new treatment approach for each stage in order to reach an optimal treatment for multiple myeloma patients.
对Merlini、Waldenstrom和Jayakar（1980年）提出的用于计算生存率的数学模型的可靠性，在一组80例多发性骨髓瘤患者中进行了测试。使用单变量回归分析比较了观察到的和计算出的生存率。结果表明，在研究患者组中，观察到的和计算出的生存率之间存在显著关系（p小于0.001）。这些观察结果证实，这个有用且可靠的临床分期系统可以作为为每个阶段制定新治疗方法个体化的基础，以便为多发性骨髓瘤患者实现最佳治疗。
