激活 ERK 活性。
Lighting Up ERK Activity.
机构信息
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
出版信息
Dev Cell. 2017 Jan 23;40(2):115-116. doi: 10.1016/j.devcel.2016.12.016.
PMID:28118596
Abstract
Activation of extracellular signal regulated kinase (ERK) is used by many signaling pathways to control tissue patterning in a broad range of multicellular organisms. In this issue of Developmental Cell, Johnson et al. (2017) provide an optogenetic approach to manipulate this pathway with high precision and explore its signaling code.
摘要
细胞外信号调节激酶 (ERK) 的激活被许多信号通路用于控制广泛的多细胞生物中的组织模式形成。在本期《发育细胞》中，Johnson 等人（2017 年）提供了一种光遗传学方法，以高精度操纵该途径，并探索其信号编码。
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