Choudhury A R, Friederichs E, Speer C P, Schröter W
Universitäts-Kinderklinik, Göttingen.
Monatsschr Kinderheilkd. 1989 Aug;137(8):458-62.
Two newborn infants with severe alloimmunothrombocytopenia due to maternal immunization against fetal PlA1-positive platelets were treated by a combination of i.v.-immunoglobulin (400 mg/kg b.w.) and a transfusion of maternal PlA1-negative platelets. In one infant this regimen was successful; the other one had to be retreated by i.v. immunoglobulin application (400 mg/kg b.w.) over a period of five days.
两名因母亲针对胎儿PlA1阳性血小板产生免疫而患有严重同种免疫性血小板减少症的新生儿,接受了静脉注射免疫球蛋白(400毫克/千克体重)和输注母亲PlA1阴性血小板的联合治疗。其中一名婴儿的治疗方案取得了成功;另一名婴儿则需要在五天内通过静脉注射免疫球蛋白(400毫克/千克体重)进行再次治疗。