精神药物对睡眠的不良影响。
Adverse Effects of Psychotropic Medications on Sleep.
作者信息
Doghramji Karl, Jangro William C
机构信息
Fellowship in Sleep Medicine, Department of Psychiatry and Human Behavior, Jefferson Sleep Disorders Center, Sidney Kimmel Medical College, Thomas Jefferson University, Walnut Towers, 5th Floor, 211 South 9th Street, Philadelphia, PA 19107, USA.
Adult Residency Training Program, Department of Psychiatry and Human Behavior, Sidney Kimmel Medical College, Thomas Jefferson University, 833 Chestnut Street, Suite 210, Philadelphia, PA 19107, USA.
出版信息
Sleep Med Clin. 2016 Dec;11(4):503-514. doi: 10.1016/j.jsmc.2016.08.001. Epub 2016 Oct 27.
Psychotropic medications such as antidepressants, antipsychotics, stimulants, and benzodiazepines are widely prescribed. Most of these medications are thought to exert their effects through modulation of various monoamines as well as interactions with receptors such as histamine and muscarinic cholinergic receptors. Through these interactions, psychotropics can also have a significant impact on sleep physiology, resulting in both beneficial and adverse effects on sleep.
抗抑郁药、抗精神病药、兴奋剂和苯二氮卓类等精神药物被广泛使用。这些药物大多被认为是通过调节各种单胺以及与组胺和毒蕈碱胆碱能受体等受体相互作用来发挥作用的。通过这些相互作用，精神药物也会对睡眠生理产生重大影响，从而对睡眠产生有益和不利的影响。
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