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使用后下方带蒂黏膜旋转皮瓣修复鼻内鼻中隔穿孔。

Endonasal septal perforation repair using posterior and inferiorly based mucosal rotation flaps.

作者信息

Dayton Steven, Chhabra Nipun, Houser Steven

机构信息

Department of Biology, Case Western Reserve University, Cleveland, OH, United States.

Louis Stokes Cleveland VA Medical Center, Cleveland, OH, United States.

出版信息

Am J Otolaryngol. 2017 Mar-Apr;38(2):179-182. doi: 10.1016/j.amjoto.2017.01.001. Epub 2017 Jan 16.

DOI:10.1016/j.amjoto.2017.01.001
PMID:28118939
Abstract

IMPORTANCE

Repair of nasal septal perforations is challenging regardless of surgical technique due to their location and the health of surrounding tissue. There is currently no surgical procedure which is completely effective in the treatment of anteriorly located perforations.

OBJECTIVE

To report a novel method of closing anterior septal perforations using an inferiorly based mucosal rotation flap and an acellular dermal interposition graft, as well as expand upon a previous series.

DESIGN

The study includes patients who underwent surgical repair for septal perforations by the senior author between 2003 and 2015.

SETTING

The study took place at MetroHealth Medical Center in Cleveland, Ohio.

PARTICIPANTS

Thirty-nine patients (15 male) with septal perforations of various size and etiology underwent endonasal repair using rotation flaps. The average age of patients was 42-years old (range 10-67years). INTERVENTION FOR CLINICAL TRIALS OR EXPOSURE FOR OBSERVATIONAL STUDIES: Five patients had perforations such that we used inferiorly based flaps, while 35 cases utilized posteriorly based flaps. Acellular dermis was used in addition to a unilateral rotation flap.

MAIN OUTCOMES AND MEASURES

The primary outcome desired was a complete closure of the septal perforation. The success, or lack thereof, was monitored after healing from surgery.

RESULTS

Thirty-seven of the forty surgical procedures demonstrated complete closure of the perforation, a 92.5% success rate. Perforations were separated based upon size. Small perforations (<1cm) had a 93.3% success rate, medium (1-2cm) 88.9%, and all seven large perforations (>2cm) were closed successfully. In addition, all five of the inferiorly based procedures resulted in complete closure of the perforation. Of the failed repairs, one required revision surgery to repair a recurring perforation, while the other two were asymptomatic following the procedure.

CONCLUSIONS AND RELEVANCE

Endonasal repair using inferiorly based mucosal rotation flaps coupled with an acellular dermal interposition graft is a valid technique for the repair of septal perforations. Posterior rotation flaps are preferred due to major septal blood supply from branches of the sphenopalatine artery, but inferiorly based flaps are also viable options for repair for perforations located in the anterior septum.

摘要

重要性

由于鼻中隔穿孔的位置及其周围组织的健康状况,无论采用何种手术技术,修复鼻中隔穿孔都具有挑战性。目前尚无一种手术方法能完全有效地治疗位于前部的穿孔。

目的

报告一种使用带蒂下翻黏膜瓣和脱细胞真皮植入物封闭前部鼻中隔穿孔的新方法,并在先前系列研究的基础上进行扩展。

设计

该研究纳入了2003年至2015年间由资深作者进行鼻中隔穿孔手术修复的患者。

地点

该研究在俄亥俄州克利夫兰的地铁健康医疗中心进行。

参与者

39例(15例男性)鼻中隔穿孔大小和病因各异的患者接受了使用旋转瓣的鼻内修复。患者的平均年龄为42岁(范围10 - 67岁)。临床试验的干预措施或观察性研究的暴露情况:5例患者的穿孔使得我们使用了带蒂下翻瓣,而35例使用了带蒂后翻瓣。除了单侧旋转瓣外还使用了脱细胞真皮。

主要结局和测量指标

期望的主要结局是鼻中隔穿孔完全闭合。术后愈合后监测其成功与否。

结果

40例手术中有37例穿孔完全闭合,成功率为92.5%。穿孔按大小分类。小穿孔(<1cm)成功率为93.3%,中等(1 - 2cm)为88.9%,所有7例大穿孔(>2cm)均成功闭合。此外,所有5例使用带蒂下翻瓣的手术均使穿孔完全闭合。在修复失败的病例中,1例需要再次手术修复复发性穿孔,而另外2例术后无症状。

结论及相关性

使用带蒂下翻黏膜瓣联合脱细胞真皮植入物进行鼻内修复是修复鼻中隔穿孔的一种有效技术。由于蝶腭动脉分支是鼻中隔的主要血供,后翻瓣是首选,但带蒂下翻瓣也是修复前鼻中隔穿孔的可行选择。

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