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The use of hollow polymer fibers for the delivery of bioactive molecules to the brain.

作者信息

Springer J E

机构信息

Department of Neurology, Hahnemann Institute of Neuroscience, Philadelphia, PA 19101-1192.

出版信息

Neurobiol Aging. 1989 Sep-Oct;10(5):640-1; discussion 648-50. doi: 10.1016/0197-4580(89)90163-2.

Abstract

Experimental studies have provided evidence that bioactive molecules can be delivered to the central nervous system through the use of hollow polymer fibers. These implantable fibers can be used for the delivery of peptide solutions or serve as a carrier device for encapsulating tissue preparations and cell suspensions. This commentary will address the use of these polymer fibers as a potential therapeutic strategy for treating neurodegenerative disorders such as Alzheimer's disease.

摘要

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