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Treating diabetes with combination of phosphodiesterase 5 inhibitors and hydroxychloroquine-a possible prevention strategy for COVID-19?
Mol Cell Biochem. 2023 Mar;478(3):679-696. doi: 10.1007/s11010-022-04520-2. Epub 2022 Aug 29.
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Anti-inflammatory and cardioprotective effects of tadalafil in diabetic mice.
PLoS One. 2012;7(9):e45243. doi: 10.1371/journal.pone.0045243. Epub 2012 Sep 21.
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Concomitant Phosphodiesterase 5 Inhibition Enhances Myocardial Protection by Inhaled Nitric Oxide in Ischemia-Reperfusion Injury.
J Pharmacol Exp Ther. 2016 Feb;356(2):284-92. doi: 10.1124/jpet.115.227850. Epub 2015 Nov 30.
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Antidiabetogenic effects of hydroxychloroquine on insulin sensitivity and beta cell function: a randomised trial.
Diabetologia. 2015 Oct;58(10):2336-43. doi: 10.1007/s00125-015-3689-2. Epub 2015 Jul 22.

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Oral nano-formulation improves pancreatic islets dysfunction lymphatic transport for antidiabetic treatment.
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New insights on the cardiovascular effects of IGF-1.
Front Endocrinol (Lausanne). 2023 Feb 9;14:1142644. doi: 10.3389/fendo.2023.1142644. eCollection 2023.
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Treating diabetes with combination of phosphodiesterase 5 inhibitors and hydroxychloroquine-a possible prevention strategy for COVID-19?
Mol Cell Biochem. 2023 Mar;478(3):679-696. doi: 10.1007/s11010-022-04520-2. Epub 2022 Aug 29.
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Repurposing New Use for Old Drug Chloroquine against Metabolic Syndrome: A Review on Animal and Human Evidence.
Int J Med Sci. 2021 May 13;18(12):2673-2688. doi: 10.7150/ijms.58147. eCollection 2021.
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Crocin attenuates oxidative stress and inflammation in myocardial infarction induced by isoprenaline via PPARγ activation in diabetic rats.
J Diabetes Metab Disord. 2020 Nov 18;19(2):1517-1525. doi: 10.1007/s40200-020-00686-y. eCollection 2020 Dec.
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Potential Effect of Hydroxychloroquine in Diabetes Mellitus: A Systematic Review on Preclinical and Clinical Trial Studies.
J Diabetes Res. 2020 Feb 27;2020:5214751. doi: 10.1155/2020/5214751. eCollection 2020.

本文引用的文献

1
Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation.
PLoS One. 2015 Dec 4;10(12):e0143771. doi: 10.1371/journal.pone.0143771. eCollection 2015.
3
Antidiabetogenic effects of hydroxychloroquine on insulin sensitivity and beta cell function: a randomised trial.
Diabetologia. 2015 Oct;58(10):2336-43. doi: 10.1007/s00125-015-3689-2. Epub 2015 Jul 22.
4
Myocardial Energy Substrate Metabolism in Heart Failure : from Pathways to Therapeutic Targets.
Curr Pharm Des. 2015;21(25):3654-64. doi: 10.2174/1381612821666150710150445.
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Heart failure in diabetes: effects of anti-hyperglycaemic drug therapy.
Lancet. 2015 May 23;385(9982):2107-17. doi: 10.1016/S0140-6736(14)61402-1.
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PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer.
Pharmacol Ther. 2015 Mar;147:12-21. doi: 10.1016/j.pharmthera.2014.10.003. Epub 2014 Oct 31.
7
A favorable effect of hydroxychloroquine on glucose and lipid metabolism beyond its anti-inflammatory role.
Ther Adv Endocrinol Metab. 2014 Aug;5(4):77-85. doi: 10.1177/2042018814547204.
9
Chronic inhibition of phosphodiesterase 5 with tadalafil attenuates mitochondrial dysfunction in type 2 diabetic hearts: potential role of NO/SIRT1/PGC-1α signaling.
Am J Physiol Heart Circ Physiol. 2014 Jun 1;306(11):H1558-68. doi: 10.1152/ajpheart.00865.2013. Epub 2014 Apr 11.
10
Hypercholesterolemic myocardium is vulnerable to ischemia-reperfusion injury and refractory to sevoflurane-induced protection.
PLoS One. 2013 Oct 4;8(10):e76652. doi: 10.1371/journal.pone.0076652. eCollection 2013.

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