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子宫切除术后静脉内平滑肌瘤病:1例非体外循环下多学科手术成功病例

Post-hysterectomy intravenous leiomyomatosis: A case of successful multidisciplinary surgery under non-extracorporeal circulation.

作者信息

Zeng Yucui, Tang Huiru, Zeng Liping, Wei Lihui, Zhang Xiaoming, Wu Ruifang

机构信息

Department of Gynecology and Obstetrics, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China.

Department of Gynecology and Obstetrics, Peking University Second Hospital, Beijing 100044, P.R. China.

出版信息

Mol Clin Oncol. 2017 Jan;6(1):39-43. doi: 10.3892/mco.2016.1074. Epub 2016 Nov 8.

DOI:10.3892/mco.2016.1074
PMID:28123726
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5245094/
Abstract

Intravenous leiomyomatosis is a rare benign disease. We here in present the case of a 39-year-old woman with a history of hysterectomy who presented with intermittent abdominal pain, palpitations and tightness of the chest. Physical examination revealed the presence of a pelvic mass of regular shape. Gynecological ultrasonography, computed tomography scans and three-dimensional (3D) cardiac ultrasonography were used to evaluate the imaging characteristics of the mass and reach a final diagnosis. The mass appeared to extend to the iliac veins, renal veins and inferior vena cava on imaging examination. The mass was successfully excised under non-extracorporeal circulation in one stage. Pathological examination of tumor samples indicated intravenous leiomyomatosis. After the operation, the symptoms were dissipated and no abnormal echo was observed in the inferior vena cava or the right atrium on 3D-cardiac ultrasonography. The patient is currently followed up without signs of recurrence. The aim of the present study was to describe in detail the diagnostic procedure and treatment in order to improve our current understanding of this disease.

摘要

静脉内平滑肌瘤病是一种罕见的良性疾病。我们在此介绍一例39岁有子宫切除史的女性患者,她出现间歇性腹痛、心悸和胸闷。体格检查发现有一个形状规则的盆腔肿块。采用妇科超声、计算机断层扫描和三维心脏超声来评估肿块的影像学特征并做出最终诊断。影像学检查显示肿块似乎延伸至髂静脉、肾静脉和下腔静脉。该肿块在非体外循环下一期成功切除。肿瘤样本的病理检查表明为静脉内平滑肌瘤病。术后症状消失,三维心脏超声检查显示下腔静脉或右心房未观察到异常回声。该患者目前正在接受随访,无复发迹象。本研究的目的是详细描述诊断过程和治疗方法,以增进我们目前对这种疾病的了解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/5245094/a2ab636056ac/mco-06-01-0039-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/5245094/6f0c4935807c/mco-06-01-0039-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/5245094/a9881d8f4e9d/mco-06-01-0039-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/5245094/8994282a489f/mco-06-01-0039-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/5245094/a2ab636056ac/mco-06-01-0039-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/5245094/6f0c4935807c/mco-06-01-0039-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/5245094/a9881d8f4e9d/mco-06-01-0039-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/5245094/8994282a489f/mco-06-01-0039-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/5245094/a2ab636056ac/mco-06-01-0039-g03.jpg

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本文引用的文献

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Mod Pathol. 2016 May;29(5):500-10. doi: 10.1038/modpathol.2016.36. Epub 2016 Feb 19.
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Computerized tomography angiography in preoperative assessment of intravenous leiomyomatosis extending to inferior vena cava and heart.计算机断层血管造影术在术前评估累及下腔静脉及心脏的静脉内平滑肌瘤病中的应用
BMC Cancer. 2016 Feb 8;16:73. doi: 10.1186/s12885-016-2112-9.
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Treatment of Intravenous Leiomyomatosis with Cardiac Extension following Incomplete Resection.
机器人辅助子宫肌瘤切除术联合电动粉碎器术后播散性平滑肌瘤病:一例报告
Cureus. 2024 Dec 18;16(12):e75971. doi: 10.7759/cureus.75971. eCollection 2024 Dec.
不完全切除后伴心脏受累的静脉内平滑肌瘤病的治疗
Int J Vasc Med. 2015;2015:756141. doi: 10.1155/2015/756141. Epub 2015 Dec 10.
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Morphology and Immunohistochemistry for 2SC and FH Aid in Detection of Fumarate Hydratase Gene Aberrations in Uterine Leiomyomas From Young Patients.2SC和FH的形态学及免疫组织化学有助于检测年轻患者子宫平滑肌瘤中的延胡索酸水合酶基因异常。
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