Zhou Nengneng, Liu Jing, Yan Zhongfei, Wu Zhongkai, Zhang Honglin, Li Weipeng, Zhu Chengjian
State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China.
Chem Commun (Camb). 2017 Feb 7;53(12):2036-2039. doi: 10.1039/c6cc09863k.
A general and efficient visible-light photoredox-catalyzed cascade annulation of 2-ethynylaldehyde hydrazones with α-bromo-carbonyls for the synthesis of various cyclohexylidene-hydrazine-fused polycyclic compounds is described. This protocol is characterized by a broad substrate scope, mild conditions and amenability to gram-scale synthesis.
本文描述了一种通用且高效的可见光光氧化还原催化的2-乙炔基醛腙与α-溴代羰基化合物的串联环化反应，用于合成各种环己叉基肼稠合的多环化合物。该方法具有底物范围广、条件温和且适用于克级规模合成的特点。
