Dahm L J, Schaefer S D, Carder H M, Vellios F
Cancer. 1978 Nov;42(5):2343-51. doi: 10.1002/1097-0142(197811)42:5<2343::aid-cncr2820420535>3.0.co;2-0.
A case of osteosarcoma arising in the soft tissue of the larynx in an elderly man is presented with light and electron microscopic documentation. The patient developed chronic hoarseness and a recurring polypoid laryngeal tumor, causing acute airway obstruction. He was treated by total laryngectomy, but he died with multiple pulmonary metastases within three months of laryngectomy. This is the third (or possibly fourth) recorded case of osteosarcoma arising in the soft tissues of the larynx, and the previous cases were clinically and pathologically similar to this one. The prognosis of sarcoma of the larynx is poor but may be improved with early recognition and adequate surgical excision.
本文报告一例老年男性喉软组织骨肉瘤病例，并提供光镜和电镜资料。患者出现慢性声音嘶哑及复发性息肉样喉部肿瘤，导致急性气道梗阻。他接受了全喉切除术治疗，但在喉切除术后三个月内死于多处肺转移。这是第三例（也可能是第四例）有记录的喉软组织骨肉瘤病例，之前的病例在临床和病理上与本病例相似。喉肉瘤预后较差，但早期诊断并进行充分的手术切除可能改善预后。
