阴道pH值：胎膜早破的一个指标。
Vaginal pH: a marker of preterm premature rupture of the membranes.
作者信息
Ernest J M, Meis P J, Moore M L, Swain M
机构信息
Department of Obstetrics and Gynecology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
出版信息
Obstet Gynecol. 1989 Nov;74(5):734-8.
Preterm premature rupture of the membranes (PROM) is a common predecessor of preterm or low birth weight (LBW) birth, yet the risk of preterm PROM is presently unpredictable. Numerous infectious organisms that change the normal vaginal milieu have been associated with preterm PROM. Because these organisms alter vaginal pH, the use of pH was evaluated as a potential marker for women at increased risk for preterm PROM. Among 115 women at high risk for an LBW birth, those with a mean vaginal pH above 4.5 had a threefold increased risk of preterm PROM as compared with those with a mean pH of 4.5 or lower. Vaginal pH may be a useful marker to predict a woman's risk for preterm PROM.
胎膜早破（PPROM）是早产或低出生体重（LBW）出生的常见先兆，但目前早产PPROM的风险尚无法预测。许多改变正常阴道环境的感染性生物体都与早产PPROM有关。由于这些生物体改变了阴道pH值，因此将pH值作为早产PPROM风险增加女性的潜在标志物进行了评估。在115名有低出生体重风险的高危女性中，平均阴道pH值高于4.5的女性发生早产PPROM的风险是平均pH值为4.5或更低的女性的三倍。阴道pH值可能是预测女性早产PPROM风险的有用标志物。
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