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保留生育功能手术是否是绝经前无性细胞瘤患者的一种治疗选择?

Is fertility sparing surgery a treatment option for premenopausal patients with dysgerminoma?

作者信息

Iavazzo C, Vorgias G, Iavazzo P E, Gkegkes I D

出版信息

Bratisl Lek Listy. 2016;117(12):738-740. doi: 10.4149/BLL_2016_131.

Abstract

Dysgerminoma is the most common ovarian germ cell type ovarian tumour. Primarily, it presents in young women at reproductive age and thus, the preservation of fertility is considered to be fundamental when it is possible for these patients. In comparison to the past the restriction of the extent of the surgical procedure as well as the introduction of innovative chemotherapeutic regimens improved significantly both, the prognosis and the clinical outcomes of this rare neoplasia. As dysgerminomas are extremely radio- and chemosensitive, fertility sparing approach and less aggressive operations should be favoured. We present a narrative review of the multispecialty fertility sparing surgical and medical approach for women with dysgerminoma (Ref. 21).

摘要

无性细胞瘤是最常见的卵巢生殖细胞类型的卵巢肿瘤。主要发生于育龄期年轻女性,因此,对于这些患者,在可能的情况下保留生育功能被认为是至关重要的。与过去相比,手术范围的限制以及创新化疗方案的引入显著改善了这种罕见肿瘤的预后和临床结局。由于无性细胞瘤对放疗和化疗极为敏感,应优先采用保留生育功能的方法和侵袭性较小的手术。我们对无性细胞瘤女性患者多学科保留生育功能的手术和医学方法进行了叙述性综述(参考文献21)。

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