Anhui Provincial Key Lab of Photonics Devices and Materials, Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031, China.
Analyst. 2017 Feb 14;142(4):596-602. doi: 10.1039/c6an02414a. Epub 2017 Jan 27.
A surface-enhanced Raman scattering (SERS) tapered fiber probe has been developed by using a chemically-etched tapered fiber tip and silanization of the surface of the fiber taper, followed by the hydrothermal growth of silver nanoparticles (AgNPs) on the silanized fiber taper. 4-Aminothiophenol (4-ATP) was selected as the target analyte to study the SERS responses of the prepared fiber SERS probe in an optrode remote detection mode. The experimental results show that the prepared fiber probe exhibited the ability to detect the 4-ATP molecule at a concentration as low as 10 M and good reproducibility with the relative standard deviation (RSD) values being less than 9.1% for the strongest Raman peak. This work gives a novel and reliable way to realize a fiber SERS probe with high sensitivity, long-term stability, good reproducibility, and superior recyclability, exhibiting potential in SERS-based in situ detection application.
一种基于表面增强拉曼散射（SERS）的锥形光纤探针，通过化学刻蚀锥形光纤尖端和光纤锥表面的硅烷化处理，随后在硅烷化光纤锥上进行银纳米粒子（AgNPs）的水热生长来制备。选择 4-巯基苯胺（4-ATP）作为目标分析物，以研究在光极远程检测模式下制备的光纤 SERS 探针的 SERS 响应。实验结果表明，所制备的光纤探针具有检测低至 10 μM 浓度的 4-ATP 分子的能力，并且具有良好的重现性，最强拉曼峰的相对标准偏差（RSD）值小于 9.1%。这项工作为实现具有高灵敏度、长期稳定性、良好重现性和优异可回收性的光纤 SERS 探针提供了一种新颖可靠的方法，在基于 SERS 的原位检测应用中具有潜在的应用前景。
