Pichler Hefti Jacqueline, Hoigné-Perret Philipp, Kottke Raimund
1 Division of Pneumology, Inselspital University and University Hospital Bern , Bern, Switzerland .
2 Kardiologische Gemeinschaftspraxis Bern , Bern, Switzerland .
High Alt Med Biol. 2017 Jun;18(2):182-184. doi: 10.1089/ham.2016.0103. Epub 2017 Jan 27.
Pichler Hefti, Jacqueline, Philipp Hoigné-Perret, and Raimund Kottke. Extensive microhemorrhages of the cerebellar peduncles after high-altitude cerebral edema. High Alt Med Biol. 18:182-184, 2017.-Neuromagnetic resonance imaging (MRI) of subjects who suffered from high-altitude cerebral edema (HACE) typically shows cerebral microhemorrhages (MH) of the corpus callosum, in particular the splenium, and supratentorial white matter. This is a case report of a 43-year-old male, who suffered from unusually prolonged severe ataxia and amnesia after having been rescued during the ascent to Mount Everest at 6400 m. MRI of the brain 63 days after the incident showed the typical MH in the corpus callosum, but, in addition, extensive MH were found in the middle cerebellar peduncles. These infratentorial MH might reflect the pronounced atactic gait disorder. This case describes the first HACE-associated MH in the cerebellar peduncles in a high-altitude mountaineer indicating a potential vulnerability of infratentorial brain areas to hypobaric hypoxia.
皮希勒·赫夫蒂、杰奎琳、菲利普·霍伊内-佩雷、雷蒙德·科特克。高原脑水肿后小脑脚广泛微出血。《高原医学与生物学》。2017年第18卷:182 - 184页。——高原脑水肿(HACE)患者的神经磁共振成像(MRI)通常显示胼胝体,特别是压部,以及幕上白质的脑微出血(MH)。本文报告了一例43岁男性病例,该患者在攀登珠穆朗玛峰至6400米处获救后,出现了异常长时间的严重共济失调和失忆。事件发生63天后的脑部MRI显示胼胝体有典型的微出血,但此外,在小脑中脚发现了广泛的微出血。这些幕下微出血可能反映了明显的共济失调步态障碍。该病例描述了首例高原登山者中与高原脑水肿相关的小脑脚微出血,表明幕下脑区对低压缺氧可能存在易损性。