Kimbrel Nathan A, Newins Amie R, Dedert Eric A, Van Voorhees Elizabeth E, Elbogen Eric B, Naylor Jennifer C, Ryan Wagner H, Brancu Mira, Beckham Jean C, Calhoun Patrick S
Durham Veterans Affairs Medical Center, Durham, NC, USA; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA.
University of Central Florida, Orlando, FL, USA.
J Psychiatr Res. 2017 Jun;89:1-5. doi: 10.1016/j.jpsychires.2017.01.002. Epub 2017 Jan 5.
The objective of the present research was to examine the association between lifetime cannabis use disorder (CUD), current suicidal ideation, and lifetime history of suicide attempts in a large and diverse sample of Iraq/Afghanistan-era veterans (N = 3233) using a battery of well-validated instruments. As expected, CUD was associated with both current suicidal ideation (OR = 1.683, p = 0.008) and lifetime suicide attempts (OR = 2.306, p < 0.0001), even after accounting for the effects of sex, posttraumatic stress disorder, depression, alcohol use disorder, non-cannabis drug use disorder, history of childhood sexual abuse, and combat exposure. Thus, the findings from the present study suggest that CUD may be a unique predictor of suicide attempts among Iraq/Afghanistan-era veterans; however, a significant limitation of the present study was its cross-sectional design. Prospective research aimed at understanding the complex relationship between CUD, mental health problems, and suicidal behavior among veterans is clearly needed at the present time.
本研究的目的是，使用一系列经过充分验证的工具，在一个规模庞大且多样化的伊拉克/阿富汗战争时期退伍军人样本（N = 3233）中，考察终生大麻使用障碍（CUD）、当前自杀意念和自杀未遂终生史之间的关联。正如预期的那样，即使在考虑了性别、创伤后应激障碍、抑郁症、酒精使用障碍、非大麻药物使用障碍、儿童期性虐待史和战斗暴露的影响之后，CUD仍与当前自杀意念（比值比[OR]=1.683，p = 0.008）和终生自杀未遂（OR = 2.306，p < 0.0001）相关。因此，本研究结果表明，CUD可能是伊拉克/阿富汗战争时期退伍军人自杀未遂的一个独特预测因素；然而，本研究的一个重大局限是其横断面设计。目前显然需要开展前瞻性研究，以了解退伍军人中CUD、心理健康问题和自杀行为之间的复杂关系。
