ANAQUIN：用于下一代测序中掺入对照分析的软件工具包。
ANAQUIN: a software toolkit for the analysis of spike-in controls for next generation sequencing.
作者信息
Wong Ted, Deveson Ira W, Hardwick Simon A, Mercer Tim R
机构信息
Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, NSW, Australia.
Faculty of Science, School of Biotechnology and Biomolecular Sciences, UNSW, Sydney, NSW, Australia.
出版信息
Bioinformatics. 2017 Jun 1;33(11):1723-1724. doi: 10.1093/bioinformatics/btx038.
SUMMARY
Spike-in controls are synthetic nucleic-acid sequences that are added to a user's sample and constitute internal standards for subsequent steps in the next generation sequencing workflow.
AVAILABILITY AND IMPLEMENTATION
: The software is implemented in C ++/R and is freely available under BSD license. The source code is available from github.com/student-t/Anaquin , binaries and user manual from www.sequin.xyz/software and R package from bioconductor.org/packages/Anaquin.
CONTACT
anaquin@garvan.org.au or t.mercer@garvan.org.au.
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
摘要
掺入对照是添加到用户样本中的合成核酸序列，构成了下一代测序工作流程后续步骤的内标。
可用性和实现方式
该软件用C++/R实现，根据BSD许可免费提供。源代码可从github.com/student-t/Anaquin获取，二进制文件和用户手册可从www.sequin.xyz/software获取，R包可从bioconductor.org/packages/Anaquin获取。
联系方式
anaquin@garvan.org.au或t.mercer@garvan.org.au。
补充信息
补充数据可在《生物信息学》在线获取。
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