Division of Endocrinology, Department of Medicine, New York Presbyterian Hospital, Weill Cornell Medical College, 211 East 80th Street, New York, NY 10075, USA.
Endocrinol Metab Clin North Am. 2017 Mar;46(1):105-116. doi: 10.1016/j.ecl.2016.09.011. Epub 2016 Nov 25.
Most metabolic effects following bariatric surgery are favorable. One area in which the consequences seem to be detrimental is on skeletal health. Mechanisms that have been cited include malabsorption of calcium and vitamin D, decrease in mechanical loading, and changes in gastrointestinal and fat-derived hormone levels. It is important that the impact of these procedures on bone metabolism is closely examined. The significance of the bone loss that occurs, and its possible effect on future fracture risk, should also be evaluated.
大多数减重手术后的代谢效应是有利的。但在骨骼健康方面，其后果似乎是有害的。据报道，其机制包括钙和维生素 D 吸收不良、机械负荷减少以及胃肠道和脂肪来源激素水平的变化。因此，仔细检查这些手术对骨骼代谢的影响非常重要。还应评估发生的骨质流失的重要性及其对未来骨折风险的可能影响。
